1995
Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion.
Pritchard K, Groszek L, Smalley D, Sessa W, Wu M, Villalon P, Wolin M, Stemerman M. Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion. Circulation Research 1995, 77: 510-8. PMID: 7543827, DOI: 10.1161/01.res.77.3.510.Peer-Reviewed Original ResearchConceptsLow-density lipoproteinNative low-density lipoproteinN-LDLNitro-L-arginine methyl esterNitric oxideLevels of nitrotyrosineEndothelial cell releaseEC releaseThiobarbituric acid substancesFormation of peroxynitriteSuperoxide anionENOS activityL-arginineNO productionSKF-525ANitrite productionOxidative metabolism
1994
The Nitric Oxide Synthase Family of Proteins
Sessa W. The Nitric Oxide Synthase Family of Proteins. Journal Of Vascular Research 1994, 31: 131-143. PMID: 7511942, DOI: 10.1159/000159039.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid OxidoreductasesAmino Acid SequenceAnimalsArginineCardiovascular SystemCloning, MolecularConsensus SequenceDNAGene Expression Regulation, EnzymologicHumansImmune SystemMolecular Sequence DataNervous SystemNitric OxideNitric Oxide SynthasePhosphorylationSequence AlignmentSequence Homology, Amino AcidConceptsCytochrome P450 reductase domainNitric oxide synthaseP450 reductase domainNitric oxide synthase (NOS) familySynthase familyMammalian enzymeSeparate genesReductase domainMolecular biologyNovel familyIsoforms of NOSImportant familyNitric oxideProteinEndothelial nitric oxide synthaseEnzyme nitric oxide synthaseGuanidino nitrogenImportant bio-regulatory moleculeOxide synthaseFamilyL-arginineCardiovascular systemRecent advancesGenesEnzymology
1990
Inhibition by l‐glutamine of the release of endothelium‐derived relaxing factor from cultured endothelial cells
Hecker M, Mitchell J, Swierkosz T, Sessa W, Vane J. Inhibition by l‐glutamine of the release of endothelium‐derived relaxing factor from cultured endothelial cells. British Journal Of Pharmacology 1990, 101: 237-239. PMID: 2257431, PMCID: PMC1917688, DOI: 10.1111/j.1476-5381.1990.tb12693.x.Peer-Reviewed Original Research