2017
B7-DC (PD-L2) costimulation of CD4+ T-helper 1 response via RGMb
Nie X, Chen W, Zhu Y, Huang B, Yu W, Wu Z, Guo S, Zhu Y, Luo L, Wang S, Chen L. B7-DC (PD-L2) costimulation of CD4+ T-helper 1 response via RGMb. Cellular & Molecular Immunology 2017, 15: 888-897. PMID: 28479601, PMCID: PMC6207567, DOI: 10.1038/cmi.2017.17.Peer-Reviewed Original ResearchConceptsRepulsive guidance molecule bT cell responsesB7-DCPD-1T cellsB7-DC/PDCoinhibitory receptor PD-1T helper 1 responseTh2-mediated asthmaSmall airway inflammationReceptor PD-1T cell inhibitionExperimental mouse modelNaive mouse T cellsMouse T cellsAirway inflammationTh1 polarizationTh1 responseDendritic cellsLung pathologyMouse modelCostimulatory functionCostimulatory receptorsCD4Costimulation
2012
[Experimental study of inhibition of tumor cell proliferation by a novel gene SPATA12].
Liu Z, Lin Y, Liu X, Yu W, Zhang Y, Li D. [Experimental study of inhibition of tumor cell proliferation by a novel gene SPATA12]. Journal Of Central South University. Medical Sciences. 2012, 37: 222-7. PMID: 22561491, DOI: 10.3969/j.issn.1672-7347.2012.03.002.Peer-Reviewed Original ResearchConceptsTumor cell proliferationTesticular tumorsCell proliferationColony formationReverse transcription-polymerase chainSitu hybridization analysisTranscription-polymerase chainNormal adult testisDevelopment of tumorsDiphenyl tetrazolium bromideCell cycle genesTissue microarrayCyclin D1MRNA expressionTumor cellsInhibitory roleCyclin A1 geneCyclin E1RT-PCRTumorsDimethylthiazol-2MTT assayTetrazolium bromideCyclin B1Expression levels