Sulfasalazine induces autophagy inhibiting neointimal hyperplasia following carotid artery injuries in mice
Zhang W, Yan C, Xiao Y, Sun Y, Lin Y, Li Q, Cai W. Sulfasalazine induces autophagy inhibiting neointimal hyperplasia following carotid artery injuries in mice. Frontiers In Bioengineering And Biotechnology 2023, 11: 1199785. PMID: 37288359, PMCID: PMC10242098, DOI: 10.3389/fbioe.2023.1199785.Peer-Reviewed Original ResearchVascular smooth muscle cellsNeointimal hyperplasiaTreatment groupsSmooth muscle cellsLigation injurySSZ groupWestern blottingControl groupMuscle cellsExpression levelsVascular smooth muscle cell proliferationLC3-IILC3-II expression levelsCarotid ligation injurySmooth muscle cell proliferationCarotid artery injuryCell nuclear antigen expressionPrevention of restenosisRatio of intimaCell proliferationMuscle cell proliferationP62 protein expressionNuclear antigen expressionPhosphorylation of mTORArtery injury