Microneedling as an adjuvant to topical therapies for melasma: A systematic review and meta-analysis
Bailey AJM, Li HO, Tan MG, Cheng W, Dover JS. Microneedling as an adjuvant to topical therapies for melasma: A systematic review and meta-analysis. Journal Of The American Academy Of Dermatology 2021, 86: 797-810. PMID: 33857549, DOI: 10.1016/j.jaad.2021.03.116.Peer-Reviewed Original ResearchConceptsTreatment of melasmaTopical therapyMelasma severitySystematic reviewSerious adverse eventsTopical tranexamic acidEfficacy of microneedlingPlatelet-rich plasmaAdverse eventsTopical interventionsTopical medicationsTranexamic acidProspective studyEligible studiesRadiofrequency microneedlingPRISMA guidelinesTherapyMicroneedlingMelasmaStudy designVitamin CAdjuvantWeeksDepigmenting agentTreatmentDoes N-Terminal Pro-B-Type Natriuretic Peptide Improve the Risk Stratification of Emergency Department Patients With Syncope?
Thiruganasambandamoorthy V, McRae AD, Rowe BH, Sivilotti MLA, Mukarram M, Nemnom MJ, Booth RA, Calder LA, Stiell IG, Wells GA, Cheng W, Taljaard M. Does N-Terminal Pro-B-Type Natriuretic Peptide Improve the Risk Stratification of Emergency Department Patients With Syncope? Annals Of Internal Medicine 2020, 172: 648-655. PMID: 32340039, DOI: 10.7326/m19-3515.Peer-Reviewed Original ResearchConceptsCanadian Syncope Risk ScoreSerious adverse eventsPro-B-type natriuretic peptideSerum NT-proBNP concentrationNT-proBNP concentrationsNT-proBNPNatriuretic peptideED patientsN-terminal pro-B-type natriuretic peptideTerminal pro-B-type natriuretic peptidePhysicians Services Incorporated FoundationIndex ED visitNT-proBNP valuesAdult ED patientsProspective cohort studySerum NT-proBNPEmergency department patientsNet reclassification indexHeterogeneity of outcomesAdjudication of outcomesNoncardiac eventsED dispositionAdverse eventsCohort studyComposite outcome