Featured Publications
Diagnosis of ventilator-associated pneumonia in critically ill adult patients—a systematic review and meta-analysis
Fernando SM, Tran A, Cheng W, Klompas M, Kyeremanteng K, Mehta S, English SW, Muscedere J, Cook DJ, Torres A, Ranzani OT, Fox-Robichaud AE, Alhazzani W, Munshi L, Guyatt GH, Rochwerg B. Diagnosis of ventilator-associated pneumonia in critically ill adult patients—a systematic review and meta-analysis. Intensive Care Medicine 2020, 46: 1170-1179. PMID: 32306086, PMCID: PMC7223448, DOI: 10.1007/s00134-020-06036-z.Peer-Reviewed Original ResearchConceptsVentilator-associated pneumoniaEndotracheal aspiratesChest radiographyDiagnosis of VAPBronchoscopic sampling methodsIll adult patientsPhysical examination findingsEnglish-language studiesUnnecessary antimicrobial useAdult patientsVAP diagnosisPurulent secretionsExamination findingsPhysical examinationClinical indicatorsAntibiotic treatmentHistopathological analysisStudy qualitySystematic reviewAntimicrobial usePooled sensitivityDiagnosisPneumoniaReference standardRadiography
2023
Test Characteristics of Emergency Medicine-Performed Point-of-Care Ultrasound for the Diagnosis of Acute Cholecystitis: A Systematic Review and Meta-analysis
Wilson S, Thavanathan R, Cheng W, Stuart J, Kim D, Glen P, Duigenan S, Shorr R, Woo M, Perry J. Test Characteristics of Emergency Medicine-Performed Point-of-Care Ultrasound for the Diagnosis of Acute Cholecystitis: A Systematic Review and Meta-analysis. Annals Of Emergency Medicine 2023, 83: 235-246. PMID: 37855790, DOI: 10.1016/j.annemergmed.2023.09.005.Peer-Reviewed Original ResearchEmergency physician-performed pointAcute cholecystitisCare ultrasoundSystematic reviewFinal diagnosisDiagnostic accuracyEarly surgical managementAcute abdominal painMeta-Analyses (PRISMA) guidelinesPreferred Reporting ItemsFull-text reviewTitles/abstractsReference standardPositive likelihood ratioHierarchical summary receiverNegative likelihood ratioAbdominal painLikelihood ratioClinical suspicionHospital admissionDefinitive managementSurgical managementEmergency departmentBias assessmentEligible studies
2022
Accuracy of presenting symptoms, physical examination, and imaging for diagnosis of ruptured abdominal aortic aneurysm: Systematic review and meta‐analysis
Fernando SM, Tran A, Cheng W, Rochwerg B, Strauss SA, Mutter E, McIsaac DI, Kyeremanteng K, Kubelik D, Jetty P, Nagpal SK, Thiruganasambandamoorthy V, Roberts DJ, Perry JJ. Accuracy of presenting symptoms, physical examination, and imaging for diagnosis of ruptured abdominal aortic aneurysm: Systematic review and meta‐analysis. Academic Emergency Medicine 2022, 29: 486-496. PMID: 35220634, DOI: 10.1111/acem.14475.Peer-Reviewed Original ResearchConceptsAbdominal aortic aneurysmAortic aneurysmRuptured abdominal aortic aneurysmPooled sensitivityCases of rAAADiagnosis of AAAPhysical examination signsEarly surgical interventionLife-threatening conditionClassic clinical symptomsReference standardExamination signsAbdominal painAbdominal massVascular centersBack painClinical symptomsSurgical interventionPhysical examinationIntraoperative diagnosisUrgent transferCare ultrasoundRAAACTA diagnosisSystematic review