What Is the Best Evidence to Guide Management of Acute Achilles Tendon Ruptures? A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials
Meulenkamp B, Woolnough T, Cheng W, Shorr R, Stacey D, Richards M, Gupta A, Fergusson D, Graham ID. What Is the Best Evidence to Guide Management of Acute Achilles Tendon Ruptures? A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials. Clinical Orthopaedics And Related Research® 2021, 479: 2119-2131. PMID: 34180874, PMCID: PMC8445578, DOI: 10.1097/corr.0000000000001861.Peer-Reviewed Original ResearchConceptsAcute Achilles tendon ruptureAchilles tendon ruptureTendon ruptureRisk of reruptureOpen surgeryLower riskFunctional rehabilitationSystematic reviewRandom-effects Bayesian networkPatient-reported outcome scoresPatient-reported outcome measuresPrimary immobilizationSmall sample sizeGrades of RecommendationOpen surgical repairRisk of complicationsMultiple treatment optionsNetwork Meta-AnalysisRandomized Controlled TrialsMeta-analysis extension statementSpecific patient populationsStudy treatment armsConsiderable clinical heterogeneityPreferred Reporting ItemsRisk of performance