2023
When a calorie is not just a calorie: Diet quality and timing as mediators of metabolism and healthy aging
Mihaylova M, Chaix A, Delibegovic M, Ramsey J, Bass J, Melkani G, Singh R, Chen Z, Ja W, Shirasu-Hiza M, Latimer M, Mattison J, Thalacker-Mercer A, Dixit V, Panda S, Lamming D. When a calorie is not just a calorie: Diet quality and timing as mediators of metabolism and healthy aging. Cell Metabolism 2023, 35: 1114-1131. PMID: 37392742, PMCID: PMC10528391, DOI: 10.1016/j.cmet.2023.06.008.Peer-Reviewed Original ResearchConceptsCalorie restrictionHealthy agingEpidemic of obesityTime-restricted feedingWhole-body metabolismMacronutrient sourcesAge-associated diseasesCardiovascular diseaseNovel therapiesMetabolic effectsMacronutrient compositionDiet qualityMedicine approachNIH workshopCaloriesMetabolic responseDiseaseMediators of metabolismDietary compositionMolecular mechanismsRecent findingsMetabolismObesityDiabetesTherapy
2019
Ketogenic diet activates protective γδ T cell responses against influenza virus infection
Goldberg E, Molony R, Sidorov S, Kudo E, Dixit V, Iwasaki A. Ketogenic diet activates protective γδ T cell responses against influenza virus infection. The Journal Of Immunology 2019, 202: 62.7-62.7. DOI: 10.4049/jimmunol.202.supp.62.7.Peer-Reviewed Original ResearchΓδ T cellsKetogenic dietIAV infectionT cellsHigh-fat high-carbohydrate dietHigh-fat ketogenic dietΓδ T cell responsesInfection-associated morbidityLethal IAV infectionT cell responsesInfluenza virus infectionAnti-viral resistanceHigh-carbohydrate dietInfluenza diseaseKD feedingNovel therapiesVirus infectionGlobal healthcare concernHepatic ketogenesisAbstract InfluenzaCell responsesHealthcare concernInfectionBarrier functionDiet