2015
Comparing clinical outcomes in HIV‐infected and uninfected older men hospitalized with community‐acquired pneumonia
Barakat LA, Juthani-Mehta M, Allore H, Trentalange M, Tate J, Rimland D, Pisani M, Akgün KM, Goetz MB, Butt AA, Rodriguez-Barradas M, Duggal M, Crothers K, Justice AC, Quagliarello VJ. Comparing clinical outcomes in HIV‐infected and uninfected older men hospitalized with community‐acquired pneumonia. HIV Medicine 2015, 16: 421-430. PMID: 25959543, PMCID: PMC5015437, DOI: 10.1111/hiv.12244.Peer-Reviewed Original ResearchConceptsCommunity-acquired pneumoniaVeterans Aging Cohort StudyVACS IndexCAP outcomesAntiretroviral therapyOlder adultsHigher VACS indexDays of dischargeAging Cohort StudyUninfected participantsCohort studyMean LOSHIV infectionLonger LOSClinical outcomesUnadjusted analysesUninfected groupMultivariable modelEligibility criteriaHIVMale veteransMortality rateART useMortalityOutcomes
2014
Outcomes among older adult liver transplantation recipients in the model of end stage liver disease (MELD) era.
Malinis MF, Chen S, Allore HG, Quagliarello VJ. Outcomes among older adult liver transplantation recipients in the model of end stage liver disease (MELD) era. Annals Of Transplantation 2014, 19: 478-87. PMID: 25256592, PMCID: PMC4201657, DOI: 10.12659/aot.890934.Peer-Reviewed Original ResearchConceptsFunctional statusHepatitis CDonor ageHepatocellular carcinomaLT recipientsMELD eraAge 50End‐stage liver disease eraFive-year graft survival ratesEnd-stage liver disease (MELD) scoreSurvival rateAdult liver transplantation recipientsStage liver disease scoreLong-term graft survivalCox proportional hazard modelingHazard modelingPre-MELD eraGraft survival ratesLiver Disease scoreRetrospective cohort studyLiver transplantation recipientsLong-term graftModifiable risk factorsAdult LT recipientsShort-term outcomes
2012
The Ability of Virulence Factor Expression by Pseudomonas aeruginosa to Predict Clinical Disease in Hospitalized Patients
Ledizet M, Murray TS, Puttagunta S, Slade MD, Quagliarello VJ, Kazmierczak BI. The Ability of Virulence Factor Expression by Pseudomonas aeruginosa to Predict Clinical Disease in Hospitalized Patients. PLOS ONE 2012, 7: e49578. PMID: 23152923, PMCID: PMC3495863, DOI: 10.1371/journal.pone.0049578.Peer-Reviewed Original ResearchConceptsP. aeruginosa infectionAeruginosa infectionBacterial factorsHospitalized patientsUrinary tractPositive P. aeruginosa culturesP. aeruginosaUrinary tract cathetersP. aeruginosa isolatesLogistic regression modelsPseudomonas aeruginosaProspective cohortDiabetes mellitusSubgroup analysisClinical dataTreatment decisionsClinical diseaseAeruginosa isolatesAnimal modelsPatientsClinical sitesFactor expressionInfectionHost factorsP. aeruginosa cultures
2001
Computed Tomography of the Head before Lumbar Puncture in Adults with Suspected Meningitis
Hasbun R, Abrahams J, Jekel J, Quagliarello V. Computed Tomography of the Head before Lumbar Puncture in Adults with Suspected Meningitis. New England Journal Of Medicine 2001, 345: 1727-1733. PMID: 11742046, DOI: 10.1056/nejmoa010399.Peer-Reviewed Original ResearchConceptsLumbar punctureAbnormal findingsNeurologic abnormalitiesCentral nervous system diseaseAbnormal visual fieldsHealth Stroke ScaleMild mass effectHistory of seizuresUnderwent lumbar punctureNervous system diseasesResults of CTMass effectNegative predictive valueBase lineStroke ScaleClinical characteristicsClinical featuresFacial palsyArm driftCT scanSystem diseasesComputed tomographyPatientsMeningitisPredictive valueCommunity-Acquired Bacterial Meningitis in Adults: Categorization of Causes and Timing of Death
McMillan D, Lin C, Aronin S, Quagliarello V. Community-Acquired Bacterial Meningitis in Adults: Categorization of Causes and Timing of Death. Clinical Infectious Diseases 2001, 33: 969-975. PMID: 11528567, DOI: 10.1086/322612.Peer-Reviewed Original ResearchConceptsCommunity-acquired bacterial meningitisBacterial meningitisTiming of deathImmediate causeSurvival end pointsWorld Health OrganizationMeningitisHealth StatisticsEnd pointUnderlying causeCategorization of causesHealth OrganizationDeathSubstantial proportionCategory IIIPatientsCategory IIAdultsCauseCategory IHospitalization
1996
Acute meningitis with a negative gram's stain: Clinical and management outcomes in 171 episodes
Elmore J, Horwitz R, Quagliarello V. Acute meningitis with a negative gram's stain: Clinical and management outcomes in 171 episodes. The American Journal Of Medicine 1996, 100: 78-84. PMID: 8579091, DOI: 10.1016/s0002-9343(96)90015-7.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdolescentAdultAnti-Bacterial AgentsBacteremiaChildCohort StudiesColoring AgentsCommunity-Acquired InfectionsComorbidityDecision MakingFemaleFeverHumansImmunocompromised HostLength of StayLeukocyte CountLyme DiseaseMagnetic Resonance ImagingMaleMeningitis, AsepticMiddle AgedNeckRetrospective StudiesSeasonsSyphilisTomography, X-Ray ComputedTreatment OutcomeConceptsAcute meningitisComorbid diseasesDiagnostic causesExamination findingsCerebrospinal fluid white blood cell countWhite blood cell countCommunity-acquired illnessPhysicians' management decisionsRetrospective cohort studyEmpiric antibiotic therapyBlood cell countNegative Gram stainMagnetic resonance imagingConcurrent comorbid diseasesEmpiric treatmentCohort studyMedian stayNeck stiffnessAntibiotic therapyClinical outcomesParaclinical dataCranial imagingEmergency departmentFrequent findingTreatable disease
1993
New Perspectives on Bacterial Meningitis
Quagliarello V, Scheid W. New Perspectives on Bacterial Meningitis. Clinical Infectious Diseases 1993, 17: 603-610. PMID: 8268338, DOI: 10.1093/clinids/17.4.603.Peer-Reviewed Original ResearchGroup B Streptococcal Meningitis in Adults
DUNNE D, QUAGLIARELLO V. Group B Streptococcal Meningitis in Adults. Medicine 1993, 72: 1-10. PMID: 8426534, DOI: 10.1097/00005792-199301000-00001.Peer-Reviewed Original ResearchConceptsGroup B streptococcal meningitisStreptococcal meningitisPercent of patientsCo-morbid illnessHours of symptomsBimodal age distributionConcomitant bacteremiaUnderlying illnessGBS infectionUncommon causeImmunocompromised hostOverall mortalityClinical presentationPyogenic organismsAdult casesRetrospective analysisMeningitisFrequent entityPatientsAdultsIllnessAge distributionHigh percentageBacteremiaImmunocompetent