2015
The Microbiota and Microbiome in Aging: Potential Implications in Health and Age‐Related Diseases
Zapata HJ, Quagliarello VJ. The Microbiota and Microbiome in Aging: Potential Implications in Health and Age‐Related Diseases. Journal Of The American Geriatrics Society 2015, 63: 776-781. PMID: 25851728, PMCID: PMC4406803, DOI: 10.1111/jgs.13310.Peer-Reviewed Original ResearchConceptsOlder adultsClostridium difficile colitisDevelopment of comorbiditiesCommensal bacterial communityDifficile colitisVulvovaginal atrophyProinflammatory stateAtherosclerotic diseaseClinical changesColorectal carcinomaPhysical frailtyClinical problemLocation of residenceGut microbiotaDeoxyribonucleic acid sequencingHealthy adultsAccompany agingBasal levelsAdultsMicrobiotaDiseaseMicrobiomeColitisComorbiditiesPotential implications
2010
Infectious Diseases in the Nursing Home Setting: Challenges and Opportunities for Clinical Investigation
High K, Juthani-Mehta M, Quagliarello V. Infectious Diseases in the Nursing Home Setting: Challenges and Opportunities for Clinical Investigation. Clinical Infectious Diseases 2010, 51: 931-936. PMID: 20822459, PMCID: PMC3083824, DOI: 10.1086/656411.Peer-Reviewed Original ResearchConceptsNursing home residentsHome residentsInfectious diseasesNursing homesNursing home settingMultiple comorbid diseasesPublic health problemComorbid diseasesHigh prevalenceFunctional declineClinical investigationPhysician investigatorsHealth problemsDiseaseHome settingOlder AmericansUnique issuesResidentsImmunosenescencePrognosisDementiaInfectionPrevalenceDiagnosis
2004
Prognostic Scoring Systems for Infectious Diseases: Their Applicability to the Care of Older Adults
High K, Juthani-Mehta M, Quagliarello V. Prognostic Scoring Systems for Infectious Diseases: Their Applicability to the Care of Older Adults. Clinical Infectious Diseases 2004, 38: 692-696. PMID: 14986254, DOI: 10.1086/381688.Peer-Reviewed Original ResearchConceptsPrognostic scoring systemOlder adultsScoring systemAdult populationInfectious diseasesPrimary end pointNumber of patientsGeneral adult populationHealth care needsHealth care costsHeterogeneous adult populationClinical outcomesBloodstream infectionsIndividual patientsCare needsCare costsRelevant outcomesEnd pointClinical predictionDiseasePatientsAdultsFurther investigationCareOutcomes
2001
Utility of prognostic stratification in adults with community-acquired bacterial meningitis
Aronin S, Quagliarello V. Utility of prognostic stratification in adults with community-acquired bacterial meningitis. Comprehensive Therapy 2001, 27: 72-77. PMID: 11280860, DOI: 10.1007/s12019-001-0011-7.Peer-Reviewed Original ResearchNew Perspectives on Pneumococcal Meningitis
Aronin S, Quagliarello V. New Perspectives on Pneumococcal Meningitis. Hospital Practice 2001, 36: 43-51. PMID: 11220360, DOI: 10.3810/hp.2001.02.228.Peer-Reviewed Original Research
1996
Prevention and Treatment of Cryptococcal Meningitis in Patients with AIDS
Villanueva M, Quagliarello V. Prevention and Treatment of Cryptococcal Meningitis in Patients with AIDS. CNS Drugs 1996, 5: 246-256. DOI: 10.2165/00023210-199605040-00003.Peer-Reviewed Original ResearchCryptococcal meningitisClinical studiesAggressive initial treatmentLifelong suppressive therapyProspective clinical studySuppressive therapyProlonged immunosuppressionFungal meningitisClinical presentationInitial treatmentRare diagnosisTreatment strategiesAmphotericin BOptimal managementMeningitisPatientsAIDS epidemicTreatmentAIDSDiseaseImmunosuppressionHIVTherapyDiagnosisFluconazole