1996
Prevention and Treatment of Cryptococcal Meningitis in Patients with AIDS
Villanueva M, Quagliarello V. Prevention and Treatment of Cryptococcal Meningitis in Patients with AIDS. CNS Drugs 1996, 5: 246-256. DOI: 10.2165/00023210-199605040-00003.Peer-Reviewed Original ResearchCryptococcal meningitisClinical studiesAggressive initial treatmentLifelong suppressive therapyProspective clinical studySuppressive therapyProlonged immunosuppressionFungal meningitisClinical presentationInitial treatmentRare diagnosisTreatment strategiesAmphotericin BOptimal managementMeningitisPatientsAIDS epidemicTreatmentAIDSDiseaseImmunosuppressionHIVTherapyDiagnosisFluconazole
1995
Primary prevention of cryptococcal meningitis by fluconazole in HIV-infected patients
Quagliarello V, Viscoli C, Horwitz R. Primary prevention of cryptococcal meningitis by fluconazole in HIV-infected patients. The Lancet 1995, 345: 548-552. PMID: 7776774, DOI: 10.1016/s0140-6736(95)90465-4.Peer-Reviewed Original ResearchConceptsHIV outpatient clinicCryptococcal meningitisFirst episodeCD4 countLumbar punctureUrban HIV outpatient clinicMean CD4 countUniversity Teaching HospitalCase-control studyOral fluconazolePrevious AIDSAntiretroviral therapyCryptococcal antigenCD4 cellsPrimary preventionProtective efficacyControl subjectsInsurance statusOdds ratioOral candidosisTeaching hospitalNumber of visitsCerebrospinal fluidMeningitisHIV