1986
The effect of combined modality therapy on local control and survival
DeVita V, Lippman M, Hubbard S, Ihde D, Rosenberg S. The effect of combined modality therapy on local control and survival. International Journal Of Radiation Oncology • Biology • Physics 1986, 12: 487-501. PMID: 3009367, DOI: 10.1016/0360-3016(86)90056-8.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic Combined Chemotherapy ProtocolsAnus NeoplasmsBreast NeoplasmsCarcinoma, Small CellClinical Trials as TopicCombined Modality TherapyFemaleHumansKidney NeoplasmsLung NeoplasmsLymphomaNeoplasm MetastasisNeoplasm Recurrence, LocalNeoplasmsPrognosisSarcomaSoft Tissue NeoplasmsWilms TumorConceptsLocal controlSystemic treatmentTumor typesPresence of micrometastasesEffective systemic therapyTumor cell numberLocal control measuresModality therapySystemic therapyCommon cancerMetastatic cancerLESS surgeryRadiation therapyTherapeutic programMetastatic processMicrometastasesTherapySurvivalSystemic componentCell numberTumorsMetastasis genesCancerSubstantial numberInverse relationship
1983
Progress in cancer management. Keynote address
Devita V. Progress in cancer management. Keynote address. Cancer 1983, 51: 2401-2409. PMID: 6342749, DOI: 10.1002/1097-0142(19830615)51:12+<2401::aid-cncr2820511302>3.0.co;2-7.Peer-Reviewed Original ResearchConceptsCancer managementUtility of radiotherapyUse of radiotherapyCancer cure ratesWorld War IIEradication of cancerManagement of cancerPrime therapeutic targetFirst chemotherapyNational Cancer ActBlood transfusionLocal recurrenceMedical oncologistsTreatment failureRecurrent cancerCure rateWar IIEffective treatmentTherapeutic targetPatientsRadiotherapySurgerySuch toxicitySerious cancersCancer
1980
The evolution of primary multimodality treatment in resectable breast cancer
Henney J, Devita V. The evolution of primary multimodality treatment in resectable breast cancer. Cancer 1980, 46: 999-1008. PMID: 6994877, DOI: 10.1002/1097-0142(19800815)46:4+<999::aid-cncr2820461325>3.0.co;2-e.Peer-Reviewed Original ResearchConceptsDisease-free intervalPremenopausal womenClinical trialsBreast cancerProspective randomized clinical trialsStage II breast cancerAdjuvant therapy studiesResectable breast cancerRandomized clinical trialsNational Cancer InstitutePositive resultsPostmenopausal womenMultimodality treatmentPostoperative periodPrognostic factorsNational mortalityClinical dataEstrogen receptorDrug doseCancer InstituteStage IClinical researchPatientsTherapy studiesTrials
1979
The dilemma regarding postoperative chemotherapy in primary carcinoma of the colon.
Weiss R, DeVita V. The dilemma regarding postoperative chemotherapy in primary carcinoma of the colon. Journal Of The American College Of Surgeons 1979, 149: 267-71. PMID: 380029.Peer-Reviewed Original Research
1978
Hodgkin's Disease: An Overview
LEWIS B, DeVITA V. Hodgkin's Disease: An Overview. Southern Medical Journal 1978, 71: 1546-1552. PMID: 83007, DOI: 10.1097/00007611-197812000-00029.Peer-Reviewed Original Research
1977
Malignant melanoma: prognostic factors and therapeutic results.
DeVita V, Fisher R. Malignant melanoma: prognostic factors and therapeutic results. West Virginia Medical Journal 1977, 73: 167-72. PMID: 268079.Peer-Reviewed Original Research
1976
Combination chemotherapy for advanced breast cancer: response and effect on survival.
Canellos G, DeVita V, Gold G, Chabner B, Schein P, Young R. Combination chemotherapy for advanced breast cancer: response and effect on survival. Annals Of Internal Medicine 1976, 84: 389-92. PMID: 1259283, DOI: 10.7326/0003-4819-84-4-389.Peer-Reviewed Original ResearchConceptsMedian survivalBreast cancerFunctional liver impairmentPrevious cytotoxic therapyAdvanced breast cancerMetastatic breast cancerHormonal therapyLiver impairmentMetastatic diseasePartial responseCombination chemotherapyComplete responseNodal metastasisCytotoxic therapyEndocrine ablationPatientsFourteenth daySoft tissueEighth daySurvivalTherapyCancerMonthsDaysResponsive sitesNatural history of malignant melanoma as related to therapy.
DeVita V, Fisher R. Natural history of malignant melanoma as related to therapy. Journal Of The National Cancer Institute 1976, 60: 153-7. PMID: 1260773.Peer-Reviewed Original Research
1975
Percutaneous liver biopsy, peritoneoscopy and laparotomy: an assessment of relative merits in the lymphomata.
Chabner B, Johnson R, Chretien P, Schein P, Young R, Canellos C, Hubbard S, Anderson T, Rosenoff S, DeVita V. Percutaneous liver biopsy, peritoneoscopy and laparotomy: an assessment of relative merits in the lymphomata. British Journal Of Cancer. Supplement 1975, 2: 242-7. PMID: 126693, PMCID: PMC2149568.Peer-Reviewed Original ResearchMeSH KeywordsBiopsyHumansLaparoscopyLaparotomyLiver Function TestsLiver NeoplasmsLymphomaNeoplasm MetastasisRadionuclide ImagingSpleenSplenectomyConceptsPercutaneous liver biopsyLiver biopsyLymphocytic lymphomaUntreated patientsHodgkin's lymphomaPercutaneous liver biopsy specimensStage IV diseaseConsecutive untreated patientsWedge liver biopsyLiver biopsy specimensLiver involvementPositive biopsiesBiopsy specimensPercutaneous biopsyLaparotomyPatientsBiopsyLymphomaPositive findingsTwo-thirdsFindingsDiseaseLiverCombination versus single agent chemotherapy: A review of the basis for selection of drug treatment of cancer
Devita V, Young R, Canellos G. Combination versus single agent chemotherapy: A review of the basis for selection of drug treatment of cancer. Cancer 1975, 35: 98-110. PMID: 162854, DOI: 10.1002/1097-0142(197501)35:1<98::aid-cncr2820350115>3.0.co;2-b.Peer-Reviewed Original ResearchMeSH KeywordsAdenoma, Islet CellAlkylating AgentsAntineoplastic AgentsBinding, CompetitiveBreast NeoplasmsBurkitt LymphomaChoriocarcinomaCyclophosphamideDrug ResistanceDrug Therapy, CombinationFemaleHodgkin DiseaseHumansLeukemia, LymphoidNeoplasm MetastasisNeoplasmsOvarian NeoplasmsPancreatic NeoplasmsPregnancy
1974
Indomethacin-Responsive Hypercalcemia in a Patient with Renal-Cell Adenocarcinoma
Brereton H, Halushka P, Alexander R, Mason D, Keiser H, DeVita V. Indomethacin-Responsive Hypercalcemia in a Patient with Renal-Cell Adenocarcinoma. New England Journal Of Medicine 1974, 291: 83-85. PMID: 4835887, DOI: 10.1056/nejm197407112910207.Peer-Reviewed Original ResearchTreatment of malignant melanoma with methyl CCNU
Young R, Canellos G, Chabner B, Schein P, Brereton H, DeVita V. Treatment of malignant melanoma with methyl CCNU. Clinical Pharmacology & Therapeutics 1974, 15: 617-622. PMID: 4601745, DOI: 10.1002/cpt1974156617.Peer-Reviewed Original ResearchCyclical Combination Chemotherapy for Advanced Breast Carcinoma
Canellos G, Devita V, Gold G, Chabner B, Schein P, Young R. Cyclical Combination Chemotherapy for Advanced Breast Carcinoma. The BMJ 1974, 1: 218. PMID: 4818162, PMCID: PMC1633086, DOI: 10.1136/bmj.1.5901.218.Peer-Reviewed Original ResearchConceptsMedian survivalMetastatic lesionsAdvanced metastatic breast cancerCyclical combination chemotherapyOverall median durationAdvanced breast carcinomaBone marrow involvementMetastatic breast cancerMetastasis-free intervalSoft tissueExtensive radiotherapyPrevious chemotherapyComplete remissionHaematological toxicityHormonal therapyLiver dysfunctionMarrow involvementMedian durationCombination chemotherapyEndocrine ablationBreast carcinomaBreast cancerPatientsMonthly cyclesChemotherapy
1973
Streptozotocin for malignant insulinomas and carcinoid tumor. Report of eight cases and review of the literature.
Schein P, Kahn R, Gorden P, Wells S, Devita V. Streptozotocin for malignant insulinomas and carcinoid tumor. Report of eight cases and review of the literature. JAMA Internal Medicine 1973, 132: 555-61. PMID: 4355081, DOI: 10.1001/archinte.132.4.555.Peer-Reviewed Original ResearchMeSH KeywordsAdenoma, Islet CellAdultBlood GlucoseCarcinoid TumorChemical and Drug Induced Liver InjuryCreatinineFemaleFollow-Up StudiesHumansInsulinKidneyKidney Function TestsLiverLiver NeoplasmsMaleMiddle AgedNeoplasm MetastasisPancreatic NeoplasmsProinsulinProteinuriaRadionuclide ImagingRemission, SpontaneousStreptozocinTime FactorsTolbutamideLiver‐spleen scan in hodgkin's disease
Milder M, Larson S, Bagley C, Devita V, Johnson R, Johnston G. Liver‐spleen scan in hodgkin's disease. Cancer 1973, 31: 826-834. PMID: 4706049, DOI: 10.1002/1097-0142(197304)31:4<826::aid-cncr2820310410>3.0.co;2-m.Peer-Reviewed Original ResearchConceptsLiver-spleen scanLiver involvementHodgkin's diseaseFilling defectPhysical examinationTumor involvementLiver biopsyPathologic findingsHepatic lobeLiver scanSplenic tumorAdvanced stageReliable signDiseaseSpleenTumorsScansLymphangiogramPatientsLiverInvolvementExaminationSplenomegalyBiopsyFindingsDiagnosis of liver involvement by lymphoma: Results in 96 consecutive peritoneoscopies
Bagley C, Thomas L, Johnson R, Chretien P, Devita V. Diagnosis of liver involvement by lymphoma: Results in 96 consecutive peritoneoscopies. Cancer 1973, 31: 840-847. PMID: 4267529, DOI: 10.1002/1097-0142(197304)31:4<840::aid-cncr2820310412>3.0.co;2-w.Peer-Reviewed Original ResearchConceptsHodgkin's diseaseHepatic involvementLiver biopsyPositive biopsiesHodgkin's lymphomaLymphocytic lymphomaMultiple liver biopsiesMultiple needle biopsiesPresence of hepatomegalyLiver function testsPercutaneous liver biopsyUntreated Hodgkin's diseaseFrequent false-negative resultsPresence of symptomsFalse-negative resultsLiver involvementNodal diseaseWedge biopsyLymphomatous involvementFunction testsMinimal morbidityNeedle biopsyPercutaneous biopsySame patientBiopsyOvarian carcinoma metastatic to the diaphragm—frequently undiagnosed at laparotomy A preliminary report
Bagley C, Young R, Schein P, Chabner B, Devita V. Ovarian carcinoma metastatic to the diaphragm—frequently undiagnosed at laparotomy A preliminary report. American Journal Of Obstetrics And Gynecology 1973, 116: 397-400. PMID: 4267636, DOI: 10.1016/s0002-9378(15)31299-0.Peer-Reviewed Original ResearchMeSH KeywordsBiopsyDiaphragmFemaleHumansLaparoscopyLaparotomyLiver NeoplasmsNeoplasm MetastasisOvarian NeoplasmsConceptsDiaphragmatic metastasisOvarian carcinomaOvarian carcinoma metastaticStage IA diseaseUpper abdominal metastasisIA diseaseAbdominal metastasesCarcinoma metastaticHigh incidenceMetastasisPatientsCarcinomaPreliminary reportRadiotherapyOnly siteDirect visualizationDiaphragmLaparotomyMetastaticPeritoneoscopyIncidenceDiseasePhysiciansLiverWeeksHigh-dose intermittent intravenous infusion of procarbazine (NSC-77213).
Chabner B, Sponzo R, Hubbard S, Canellos G, Young R, Schein P, Devita V. High-dose intermittent intravenous infusion of procarbazine (NSC-77213). Cancer Chemotherapy Reports 1973, 57: 361-3. PMID: 4584487.Peer-Reviewed Original Research
1972
Nonlymphomatous Malignant Tumors Complicating Hodgkin's Disease — Possible Association with Intensive Therapy
Arseneau J, Sponzo R, Levin D, Schnipper L, Bonner H, Young R, Canellos G, Johnson R, DeVita V. Nonlymphomatous Malignant Tumors Complicating Hodgkin's Disease — Possible Association with Intensive Therapy. New England Journal Of Medicine 1972, 287: 1119-1122. PMID: 5082192, DOI: 10.1056/nejm197211302872204.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAntineoplastic AgentsCarcinoma, Squamous CellCyclophosphamideDrug-Related Side Effects and Adverse ReactionsFemaleFibrosarcomaFollow-Up StudiesHead and Neck NeoplasmsHodgkin DiseaseHumansMaleMiddle AgedNeoplasm MetastasisNeoplasmsNeoplasms, Radiation-InducedNitrogen Mustard CompoundsPrednisoneProcarbazineRadiotherapyRemission, SpontaneousTime FactorsVincristineConceptsHodgkin's diseaseMalignant tumorsIntensive radiotherapyIntensive chemotherapyBiopsy-proven malignant tumorsTime of diagnosisSecond malignant tumorsRisk of developmentBasis of treatmentBasis of ageIntensive therapyCase recordsChemotherapyDiseasePatientsRadiotherapyTumorsGreater increaseSubgroupsRiskTherapyIncidenceDiagnosisLate Recurrence of Testicular Tumor
Chabner B, Canellos G, Olweny C, DeVita V. Late Recurrence of Testicular Tumor. New England Journal Of Medicine 1972, 287: 413. PMID: 5065110, DOI: 10.1056/nejm197208242870817.Peer-Reviewed Original Research