2024
Associations of alcohol and tobacco use with psychotic, depressive and developmental disorders revealed via multimodal neuroimaging
Qiu L, Liang C, Kochunov P, Hutchison K, Sui J, Jiang R, Zhi D, Vergara V, Yang X, Zhang D, Fu Z, Bustillo J, Qi S, Calhoun V. Associations of alcohol and tobacco use with psychotic, depressive and developmental disorders revealed via multimodal neuroimaging. Translational Psychiatry 2024, 14: 326. PMID: 39112461, PMCID: PMC11306356, DOI: 10.1038/s41398-024-03035-2.Peer-Reviewed Original ResearchConceptsFronto-limbic networkSalience networkAssociated with cognitionFronto-basal gangliaDevelopmental disordersBrain networksLimbic systemAlcohol useAssociated with alcohol useMultimodal brain networksTobacco useAssociation of alcoholPsychiatric disordersMultimodal neuroimagingDMNBrain featuresCognitionAlcohol/tobacco useDisordersAssociated with tobacco useDepressionSymptomsFunctional abnormalitiesAlcoholBrainReconfiguration of Structural and Functional Connectivity Coupling in Patient Subgroups With Adolescent Depression
Xu M, Li X, Teng T, Huang Y, Liu M, Long Y, Lv F, Zhi D, Li X, Feng A, Yu S, Calhoun V, Zhou X, Sui J. Reconfiguration of Structural and Functional Connectivity Coupling in Patient Subgroups With Adolescent Depression. JAMA Network Open 2024, 7: e241933. PMID: 38470418, PMCID: PMC10933730, DOI: 10.1001/jamanetworkopen.2024.1933.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdverse Childhood ExperiencesBrainCross-Sectional StudiesDepressionDepressive Disorder, MajorFemaleHumansConceptsAdolescent major depressive disorderMajor depressive disorderSC-FC couplingIncreased SC-FC couplingSC-FCMode networkSuicide attemptsFirst-episode major depressive disorderVisual networkMDD subgroupsNonsuicidal self-injurious behaviorRates of self-injuryHealthy controlsResting-state functional MRI dataMagnetic resonance imagingCross-sectional studySelf-injurious behaviorOutpatient psychiatry clinicFunctional MRI dataMajor life eventsFirst Affiliated Hospital of Chongqing Medical UniversityDepressive disorderNeurobiological mechanismsChildhood traumaSelf-injury
2023
ICA-based Individualized Differential Structure Similarity Networks for Predicting Symptom Scores in Adolescents with Major Depressive Disorder
Li X, Xu M, Jiang R, Li X, Calhoun V, Zhou X, Sui J. ICA-based Individualized Differential Structure Similarity Networks for Predicting Symptom Scores in Adolescents with Major Depressive Disorder. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2023, 00: 1-5. PMID: 38082692, DOI: 10.1109/embc40787.2023.10340456.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBrainConnectomeDepressive Disorder, MajorGray MatterHumansMagnetic Resonance ImagingConceptsMajor depressive disorderGray matter volumeDepressive disorderWhole-brain structural covariance networksConnectome-based predictive modelingAdolescent MDD patientsComplex mood disorderMeasure individual differencesDefault-mode networkStructural brain alterationsStructural covariance networksHamilton Depression ScaleHamilton Anxiety ScaleSpatially constrained ICAMDD patientsMood disordersBrain alterationsMatter volumeIndividual differencesBrain structuresCovariance networksAnxiety ScaleVisual networkDepression ScaleStructure similarity networkMulti-study evaluation of neuroimaging-based prediction of medication class in mood disorders
Salman M, Verner E, Bockholt H, Fu Z, Misiura M, Baker B, Osuch E, Sui J, Calhoun V. Multi-study evaluation of neuroimaging-based prediction of medication class in mood disorders. Psychiatry Research Neuroimaging 2023, 333: 111655. PMID: 37201216, PMCID: PMC10330565, DOI: 10.1016/j.pscychresns.2023.111655.Peer-Reviewed Original ResearchMeSH KeywordsAntipsychotic AgentsBipolar DisorderDepressive Disorder, MajorHumansMood DisordersNeuroimagingConceptsMood stabilizersMood disordersDSM-based diagnosesBipolar disorder patientsDepressive disorderDisorder patientsManic stateResponders to treatmentDepressive stateNeuroimaging dataMoodTreatment responseAntidepressantsDisordersDSMMedication classesComplex symptomsGold standardPatientsMDDSupport vector machineDiagnosisTreatmentComplex casesGeneralizabilityGroup independent components underpin responses to items from a depression scale.
Stoyanov D, Khorev V, Paunova R, Kandilarova S, Kurkin S, Calhoun V. Group independent components underpin responses to items from a depression scale. Acta Neuropsychiatrica 2023, 36: 9-16. PMID: 37088536, DOI: 10.1017/neu.2023.22.Peer-Reviewed Original ResearchMeSH KeywordsBrainBrain MappingDepressionDepressive Disorder, MajorFrontal LobeHumansMagnetic Resonance ImagingPrefrontal CortexConceptsFunctional magnetic resonance imagingGroup independent component analysisSelf-evaluation scaleFrontal gyrusCingulate cortexDepression ScaleRight superior frontal gyrusFunctional magnetic resonance imaging acquisitionHealthy controlsRight middle cingulate cortexAnterior cingulate cortexMiddle frontal gyrusSuperior frontal gyrusMiddle cingulate cortexIndependent component analysisGroup independent componentStatistical parametric mappingDepressive disorderDepressive episodeBrain circuitsBrain networksNeural network patternsDiagnostic conditionsParametric mappingGyrus
2022
Links between electroconvulsive therapy responsive and cognitive impairment multimodal brain networks in late-life major depressive disorder
Qi S, Calhoun V, Zhang D, Miller J, Deng Z, Narr K, Sheline Y, McClintock S, Jiang R, Yang X, Upston J, Jones T, Sui J, Abbott C. Links between electroconvulsive therapy responsive and cognitive impairment multimodal brain networks in late-life major depressive disorder. BMC Medicine 2022, 20: 477. PMID: 36482369, PMCID: PMC9733153, DOI: 10.1186/s12916-022-02678-6.Peer-Reviewed Original ResearchMeSH KeywordsBrainCognitive DysfunctionDepressive Disorder, MajorElectroconvulsive TherapyHumansNeurobiologyConceptsMultimodal brain networksElectroconvulsive therapyBrain networksHippocampal complexCognitive impairmentSingle site clinical trialsCognitive impairing effectsSuperior orbitofrontal cortexECT seriesMedial temporal cortexLate-life depressionHDRS reductionAntidepressant outcomesOrbitofrontal cortexNeurobiological underpinningsCognitive safetyImpairing effectsTemporal cortexOptimal pulse amplitudeCognitive outcomesCognitive AssessmentCognitive-impairmentLongitudinal multimodal imagingCognitive networksDepression