Identifying psychosis subtypes use individualized covariance structural differential networks and multi-site clustering
Ji Y, Pearlson G, Bustillo J, Kochunov P, Turner J, Jiang R, Shao W, Zhang X, Fu Z, Li K, Liu Z, Xu X, Zhang D, Qi S, Calhoun V. Identifying psychosis subtypes use individualized covariance structural differential networks and multi-site clustering. Schizophrenia Research 2023, 264: 130-139. PMID: 38128344, DOI: 10.1016/j.schres.2023.12.013.Peer-Reviewed Original ResearchPsychosis subtypesSchizoaffective disorderBipolar disorderClinical phenotypeFirst-degree relativesTemporal-occipital cortexAmygdala-hippocampusClinical symptomsNeuroimaging featuresBipolar-Schizophrenia NetworkBrain alterationsHealthy controlsIntermediate Phenotypes (B-SNIP) consortiumOccipital cortexDecreased connectivitySubtypesStructural covarianceFractional amplitudeSubtype IILow-frequency fluctuationsNeurobiological heterogeneityGreater predispositionPsychosis spectrumGroup differencesDiagnostic classificationPsychopathic traits and altered resting-state functional connectivity in incarcerated adolescent girls
Allen C, Maurer J, Gullapalli A, Edwards B, Aharoni E, Harenski C, Anderson N, Harenski K, Calhoun V, Kiehl K. Psychopathic traits and altered resting-state functional connectivity in incarcerated adolescent girls. Frontiers In Neuroimaging 2023, 2: 1216494. PMID: 37554634, PMCID: PMC10406221, DOI: 10.3389/fnimg.2023.1216494.Peer-Reviewed Original ResearchAmplitude of low-frequency fluctuationPsychopathic traitsResting-state networksLow-frequency fluctuationsAssociation of psychopathic traitsCorrelates of psychopathic traitsIncarcerated adolescent girlsResting-state fMRI scansResting-state functional connectivityElevated psychopathic traitsCognitive control networkGroup independent component analysisMode network componentsInter-network connectivityIntra-network connectivityHigh-risk adolescent girlsIndependent component analysisResting-state measuresFunctional network propertiesAdolescent girlsFMRI scanningParalimbic regionsMode networkIncarcerated boysFunctional connectivity