2019
Angiopoietin Level Trajectories in Toddlers With Severe Sepsis and Septic Shock and Their Effect on Capillary Endothelium
Pierce RW, Shabanova V, Canarie M, Pinto M, da Silva YS, Bhandari V, Giuliano JS. Angiopoietin Level Trajectories in Toddlers With Severe Sepsis and Septic Shock and Their Effect on Capillary Endothelium. Shock 2019, 51: 298-305. PMID: 30286031, PMCID: PMC6375782, DOI: 10.1097/shk.0000000000001172.Peer-Reviewed Original ResearchConceptsSevere sepsis/septic shockSepsis/septic shockTumor necrosis factorHuman dermal microvascular endothelial cellsCultured human dermal microvascular endothelial cellsSIRS/sepsisSeptic shockAngpt-1Severe sepsisAngpt-2Diagnostic biomarkersSevere sepsis/shockTertiary care pediatric hospitalEndothelial cellsAngpt-2 levelsOlder childrenSepsis/shockInflammatory response syndromeProspective observational studyTransendothelial electrical resistance measurementsDermal microvascular endothelial cellsAppropriate diagnostic biomarkersMicrovascular endothelial cellsYoung childrenEnzyme-linked immunoassay
2017
Risk factors for tracheostomy requirement in extremely low birth weight infants
Levit OL, Shabanova V, Bazzy-Asaad A, Bizzarro MJ, Bhandari V. Risk factors for tracheostomy requirement in extremely low birth weight infants. The Journal Of Maternal-Fetal & Neonatal Medicine 2017, 31: 447-452. PMID: 28139937, DOI: 10.1080/14767058.2017.1287895.Peer-Reviewed Original ResearchMeSH KeywordsAirway ExtubationCase-Control StudiesFemaleGestational AgeHumansInfantInfant, Extremely Low Birth WeightInfant, Extremely PrematureInfant, NewbornIntubation, IntratrachealMalePregnancyRespiration, ArtificialRetrospective StudiesRisk FactorsSeverity of Illness IndexTime FactorsTracheostomyConceptsLow birth weight infantsOdds of tracheostomyBirth weight infantsELBW infantsWeight infantsEndotracheal tubeRisk of tracheostomyPresence of comorbiditiesUse of steroidsCase-control studyConditional logistic regressionNumber of intubationsGreater cumulative exposureIntubation episodesTracheostomy requirementExtubation attemptGestational ageEpisodes/Risk factorsTracheostomyPrevious episodesCumulative exposurePoisson regressionCumulative daysInfants
2014
The Temporal Kinetics of Circulating Angiopoietin Levels in Children With Sepsis
Giuliano JS, Tran K, Li FY, Shabanova V, Tala JA, Bhandari V. The Temporal Kinetics of Circulating Angiopoietin Levels in Children With Sepsis. Pediatric Critical Care Medicine 2014, 15: e1-e8. PMID: 24141659, PMCID: PMC3947338, DOI: 10.1097/pcc.0b013e3182a553bb.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAngiopoietin-1Angiopoietin-2BiomarkersCase-Control StudiesChildChild, PreschoolFemaleHumansIntensive Care Units, PediatricLength of StayMalePredictive Value of TestsProspective StudiesSepsisSeverity of Illness IndexShock, SepticSystemic Inflammatory Response SyndromeTime FactorsConceptsSevere sepsis/shockSepsis/shockSystemic inflammatory response syndrome/sepsisPediatric patientsShock groupAngiopoietin-2Day 2Angiopoietin-1Days of illnessHours of admissionIll pediatric patientsInflammatory response syndromeRisk stratification scoresProspective observational studyCritical care physiciansVascular growth factorsEnzyme-linked immunosorbentAngiopoietin levelsPICU lengthPICU patientsSevere sepsisSepsis severityResponse syndromeStratification scoresCare physicians