2021
Use of Pharmacologic Prophylaxis Against Venous Thromboembolism in Hospitalized Injured Children
Mahajerin A, Petty JK, Hanson SJ, Shabanova V, Faustino EVS. Use of Pharmacologic Prophylaxis Against Venous Thromboembolism in Hospitalized Injured Children. Journal Of Pediatric Hematology/Oncology 2021, 44: e349-e357. PMID: 33885041, DOI: 10.1097/mph.0000000000002167.Peer-Reviewed Original ResearchConceptsReceipt of prophylaxisRisk of VTEVenous thromboembolismInjured childrenRisk prediction modelPharmacologic prophylaxisTrauma Quality Improvement ProgramLow molecular weight heparinHospitalized injured patientsPediatric-specific evidencePractice management guidelinesRandomized clinical trialsMolecular weight heparinQuality Improvement ProgramUnfractionated heparinWeight heparinRetrospective studyInjured patientsClinical trialsProphylaxisManagement guidelinesThromboembolismPatientsHigh rateChildren
2020
Risks of venous thrombosis and bleeding in critically ill adolescents after trauma or major surgery
Hanson SJ, Mahajerin A, Petty JK, Shabanova V, Faustino EVS. Risks of venous thrombosis and bleeding in critically ill adolescents after trauma or major surgery. Journal Of Pediatric Surgery 2020, 56: 302-308. PMID: 32713711, DOI: 10.1016/j.jpedsurg.2020.06.037.Peer-Reviewed Original ResearchConceptsCentral venous catheterizationVenous thromboembolismMajor surgeryMechanical ventilationAnatomic sitesHigh riskIll adolescentsVirtual Pediatric Systems databasePediatric intensive care unitRisk of VTERetrospective cohort studyIntensive care unitMixed-effects logistic regressionEffects logistic regressionPharmacologic prophylaxisAdjusted riskCohort studyVenous thrombosisCare unitVenous catheterizationLower riskSurgeryLevel IILogistic regressionTrauma
2019
Epidemiology of Clinically Relevant Bleeding in Critically Ill Adolescents.
Pinto MG, Shabanova V, Li S, Trakas E, Miksa M, Gertz S, Polikoff LA, Tala JA, Faustino EVS. Epidemiology of Clinically Relevant Bleeding in Critically Ill Adolescents. Pediatric Critical Care Medicine 2019, 20: 907-913. PMID: 31261231, DOI: 10.1097/pcc.0000000000002018.Peer-Reviewed Original ResearchConceptsRelevant bleedingVenous thromboembolismIll adolescentsPharmacologic prophylaxisHigh riskClinically Relevant BleedingMulticenter observational studyRandomized clinical trialsRisk of mortalityBleeding eventsTherapeutic anticoagulationMechanical ventilationPulmonary supportClinical trialsObservational studyThromboembolismBleedingAdolescents 13EpidemiologyStatistical significanceAnticoagulationProphylaxisSurgeryAdmissionAdolescents
2011
“Change, before you have to.”–Jack Welch, Former CEO, General Electric*
Faustino EV, Lawson KA, Northrup V, Higgerson RA. “Change, before you have to.”–Jack Welch, Former CEO, General Electric*. Critical Care Medicine 2011, 40: 2227-2228. PMID: 21336130, PMCID: PMC3101274, DOI: 10.1097/ccm.0b013e31820eb8a1.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge FactorsCase-Control StudiesCatheterization, Central VenousCause of DeathChildChild, PreschoolCritical CareCritical IllnessFemaleHospital MortalityHumansInfantIntensive Care Units, PediatricMalePrognosisReference ValuesRespiration, ArtificialRetrospective StudiesRisk AssessmentSex FactorsSurvival AnalysisTime FactorsTreatment OutcomeVenous ThrombosisConceptsVentilator-free daysIntensive care unitCentral venous lineDeep venous thrombosisDeep vein thrombosisIndex patientsVenous thrombosisCare unitMechanical ventilationIll childrenControl patientsVein thrombosisVenous lineIntensive care unit-free daysIntensive care unit stayPrevious prospective observational studyPediatric intensive care unitCentral venous line insertionSymptomatic venous thromboembolismVenous thrombosis studyProspective observational studyAlternative outcome measuresUnit stayVenous thromboembolismCohort study