2019
Local tumor response and survival outcomes after combined stereotactic radiosurgery and immunotherapy in non-small cell lung cancer with brain metastases.
Singh C, Qian JM, Yu JB, Chiang VL. Local tumor response and survival outcomes after combined stereotactic radiosurgery and immunotherapy in non-small cell lung cancer with brain metastases. Journal Of Neurosurgery 2019, 132: 512-517. PMID: 30771783, DOI: 10.3171/2018.10.jns181371.Peer-Reviewed Original ResearchConceptsAnti-PD-1 therapyKarnofsky performance statusBrain metastasesLung cancer patientsStereotactic radiosurgeryCT groupIT groupCancer patientsNon-small cell lung cancer patientsNon-small cell lung cancerCell lung cancer patientsAntibody-positive patientsGraded Prognostic AssessmentCox regression analysisCell lung cancerMedian survival timeLocal tumor responseWhole study groupMann-Whitney U testTerms of survivalLesional responseMedian survivalPerformance statusWorse survivalComplete response
2006
Multivariate analysis identifies factors that affect survival after stereotactic radiosurgery for brain metastases
Diluna M, King J, Knisely J, Bond J, De Lotbiniere A, Chiang V. Multivariate analysis identifies factors that affect survival after stereotactic radiosurgery for brain metastases. Journal Of Clinical Oncology 2006, 24: 11500-11500. DOI: 10.1200/jco.2006.24.18_suppl.11500.Peer-Reviewed Original ResearchCell lung carcinomaStereotactic radiosurgeryBrain metastasesCerebral metastasesSurgical resectionEsophageal cancerLung carcinomaBreast cancerNon-small cell lung carcinomaSmall cell lung carcinomaSystemic controlConnecticut Tumor RegistryLocation of metastasesNumber of metastasesPatient-related factorsTotal tumor burdenSystemic disease controlKaplan-Meier plotsSignificant independent predictorsSurvival dataTotal tumor volumeMedian survivalWorse survivalImproved survivalIndependent predictors