2022
Changes in the Inferior Vena Cava Are More Sensitive Than Venous Pressure During Fluid Removal: A Proof-of-Concept Study
Posada-Martinez EL, Cox ZL, Cano-Nieto MM, Ibarra-Marquez ND, Moreno-Villagomez J, Gudiño-Bravo P, Arias-Godinez JA, Lopez-Gil S, Madero M, Rao VS, Mebazaa A, Burkhoff D, Cowie MR, Fudim M, Damman K, Borlaug BA, Testani JM, Ivey-Miranda JB. Changes in the Inferior Vena Cava Are More Sensitive Than Venous Pressure During Fluid Removal: A Proof-of-Concept Study. Journal Of Cardiac Failure 2022, 29: 463-472. PMID: 36243338, DOI: 10.1016/j.cardfail.2022.09.012.Peer-Reviewed Original ResearchConceptsInferior vena cava diameterPeripheral venous pressureCentral venous pressureVenous pressureUltrafiltration volumeHeart failureVolume statusMean ultrafiltration volumeManagement of patientsVena cava diameterInferior vena cavaDiastolic dysfunctionCardiac dysfunctionStable hemodialysisVena cavaHemodialysis sessionFluid removalPatientsDialysisHemodialysisDysfunctionConcept studyGreater magnitudeStatusCava
2019
First in Human Experience with Direct Sodium Removal Using a Zero Sodium Peritoneal Solution
Rao V, Turner J, Mahoney D, Griffin M, Asher J, Ivey-Miranda J, Gomez N, Finkelstein F, Testani J. First in Human Experience with Direct Sodium Removal Using a Zero Sodium Peritoneal Solution. Journal Of Cardiac Failure 2019, 25: s7-s8. DOI: 10.1016/j.cardfail.2019.07.027.Peer-Reviewed Original ResearchStandard PD solutionHeart failurePeritoneal dialysisPD solutionsSignificant discomfortPeritoneal solutionsSodium removalHF animal modelsMethods 10 patientsSafety/tolerabilitySecondary efficacy endpointsPrimary endpointEfficacy endpointAdverse eventsBlood pressureSerum sodiumAlternative therapiesPeritoneal fluidPlasma glucosePlasma potassiumUltrafiltration volumeAnimal modelsIntraperitoneal volumeDSR groupVital signs