Role of Cbl-PI3K Interaction during Skeletal Remodeling in a Murine Model of Bone Repair
Scanlon V, Soung do Y, Adapala NS, Morgan E, Hansen MF, Drissi H, Sanjay A. Role of Cbl-PI3K Interaction during Skeletal Remodeling in a Murine Model of Bone Repair. PLOS ONE 2015, 10: e0138194. PMID: 26393915, PMCID: PMC4578922, DOI: 10.1371/journal.pone.0138194.Peer-Reviewed Original ResearchConceptsCbl-PI3K interactionHistomorphometric analysisFracture callusBone formationMid-diaphyseal femoral fracturePI3KNormal bone homeostasisBony callus formationSoft callus formationHealing femursFemoral fracturesWT miceOsteoclast numberBone resorptionTomography scanMurine modelOsteoblast surfaceFracture healingBone homeostasisBone volumeBone repairSkeletal remodelingMiceBiomechanical testingHigh expression