10 Single cell expression quantitative trait LOCI (EQTL) analsis of established lupus-risk loci in patient monocytes
Ghodke-Puranik Y, Zhongbo J, Fan W, Jensen M, Dorschner J, Vsetecka D, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Niewold T. 10 Single cell expression quantitative trait LOCI (EQTL) analsis of established lupus-risk loci in patient monocytes. Lupus Science & Medicine 2017, 4: a6. DOI: 10.1136/lupus-2017-000215.10.Peer-Reviewed Original ResearchCell typesFluidigm C1 systemDifferent cellular eventsRelated cell typesSLE risk lociDifferent cell typesEQTL associationsLoci interactEQTL analysisGene expressionMajor unanswered questionSingle-cell captureCellular eventsLoci influenceSame SNPLociPleiotropic effectsGenesEQTLsSPP1SNPsC1 systemLimited overlapImmune cell typesImmune system function