Inhibition of protein kinase C of human neutrophils by phosphatidylcholines
Yoshida K, Mohsenin V. Inhibition of protein kinase C of human neutrophils by phosphatidylcholines. Life Sciences 1994, 54: 515-524. PMID: 8107528, DOI: 10.1016/0024-3205(94)90001-9.Peer-Reviewed Original ResearchConceptsEffect of phosphatidylcholineProtein kinase CActivation of neutrophilsIntact neutrophilsMechanism of actionPKC activityPulmonary surfactant phospholipidsNeutrophil activationActivation of PKCKinase CNeutrophilsIntact restingTranslocation of PKCHuman neutrophilsSurfactant phospholipidsCytosolic PKC activityDistribution of PKCSuperoxide generationControl cellsPulmonary surfactantSpecific phosphatidylcholinesStimulationActivationFatty acyl moietiesInhibition