2016
Use of Household Cluster Investigations to Identify Factors Associated with Chikungunya Virus Infection and Frequency of Case Reporting in Puerto Rico
Bloch D, Roth NM, Caraballo EV, Muñoz-Jordan J, Hunsperger E, Rivera A, Pérez-Padilla J, Garcia B, Sharp TM. Use of Household Cluster Investigations to Identify Factors Associated with Chikungunya Virus Infection and Frequency of Case Reporting in Puerto Rico. PLOS Neglected Tropical Diseases 2016, 10: e0005075. PMID: 27764085, PMCID: PMC5072658, DOI: 10.1371/journal.pntd.0005075.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdolescentAdultAgedAged, 80 and overAir ConditioningAntibodies, ViralChikungunya FeverChikungunya virusChildChild, PreschoolCymbopogonDisease NotificationDisease OutbreaksEnzyme-Linked Immunosorbent AssayExanthemaFamily CharacteristicsFemaleFeverHumansInfantMaleMiddle AgedPoint-of-Care SystemsPolymerase Chain ReactionPuerto RicoYoung AdultConceptsSymptomatic CHIKV infectionRecent CHIKV infectionCHIKV infectionPublic health authoritiesChikungunya virusChikungunya patientsMedical careHealth authoritiesCase reportingAnti-CHIKV IgMAcute febrile illnessChikungunya virus infectionCare rapid diagnostic testsRapid diagnostic testsPuerto Rico DepartmentCluster investigationsAcute illnessFebrile illnessSkin rashResidents of householdsDevelopment of diseaseMultivariable analysisIllness onsetIgG antibodiesIgM ELISA
2013
Virus-Specific Differences in Rates of Disease during the 2010 Dengue Epidemic in Puerto Rico
Sharp TM, Hunsperger E, Santiago GA, Muñoz-Jordan JL, Santiago LM, Rivera A, Rodríguez-Acosta RL, Feliciano L, Margolis HS, Tomashek KM. Virus-Specific Differences in Rates of Disease during the 2010 Dengue Epidemic in Puerto Rico. PLOS Neglected Tropical Diseases 2013, 7: e2159. PMID: 23593526, PMCID: PMC3617145, DOI: 10.1371/journal.pntd.0002159.Peer-Reviewed Original ResearchConceptsAcute febrile illnessReverse transcriptase-polymerase chain reactionLaboratory-positive casesPrimary infectionDengue casesDENV-1DENV-2Anti-DENV IgM antibodiesSerum specimenMortality of dengueMosquito-transmitted dengue virusPrimary DENV infectionPassive dengue surveillance systemHealth care providersPrimary prevention interventionsTranscriptase-polymerase chain reactionOnly age groupDENV nucleic acidLaboratory diagnostic dataRates of diseaseFebrile illnessSevere dengueDENV infectionIgM antibodiesDENV antigen