2013
Predictive role of prenasal thickness and nasal bone for Down syndrome in the second trimester
Ozcan T, Özlü T, Allen J, Peterson J, Pressman E. Predictive role of prenasal thickness and nasal bone for Down syndrome in the second trimester. European Journal Of Obstetrics & Gynecology And Reproductive Biology 2013, 171: 220-224. PMID: 24044955, DOI: 10.1016/j.ejogrb.2013.08.039.Peer-Reviewed Original ResearchConceptsPrenasal thicknessNasal boneDown syndromePrediction of Down syndromeReceiver operating curve analysisTrimester ultrasound examinationPredictors of DSArea under the curveCut-off valueOperating curve analysisGestational ageNormal karyotypeUltrasound examinationFetusesGroup 2Group 1TrimesterCurve analysisPredictive roleDS casesFrontal boneBoneSyndromeAnterior edgePrediction of DS
2010
Mitral valve–tricuspid valve distance as a sonographic marker of trisomy 21
Grace D, Eggers P, Glantz J, Ozcan T. Mitral valve–tricuspid valve distance as a sonographic marker of trisomy 21. Ultrasound In Obstetrics And Gynecology 2010, 35: 172-177. PMID: 20069681, DOI: 10.1002/uog.7538.Peer-Reviewed Original ResearchConceptsMitral valve-tricuspid valve distanceMarkers of trisomyGestational ageSonographic markersTrisomy 21Cardiac defectsLinear regression analysisGestational age-specific percentilesSecond-trimester sonographic markersEffect of gestational ageRetrospective case-control studyCases of trisomyValve distanceMultiple linear regression analysisRegression analysisCase-control studyAge-specific percentilesWeeks gestationControl fetusesSecond-trimesterTricuspid valveVentricular septumFalse-positive rateTrisomyFetuses