2012
Regulation of glomerulotubular balance. I. Impact of dopamine on flow-dependent transport
Du Z, Yan Q, Wan L, Weinbaum S, Weinstein A, Wang T. Regulation of glomerulotubular balance. I. Impact of dopamine on flow-dependent transport. American Journal Of Physiology. Renal Physiology 2012, 303: f386-f395. PMID: 22552936, PMCID: PMC3433864, DOI: 10.1152/ajprenal.00531.2011.Peer-Reviewed Original ResearchMeSH Keywords8-Bromo Cyclic Adenosine MonophosphateAlgorithmsAnimalsBenzazepinesBicarbonatesBiological Transport, ActiveChloridesCyclic AMP-Dependent Protein KinasesDopamineDopamine AntagonistsDopamine D2 Receptor AntagonistsFemaleIsoquinolinesKidney GlomerulusKidney TubulesKidney Tubules, ProximalMacrolidesMiceMicrovilliProton-Translocating ATPasesReceptors, Dopamine D1SodiumSulfonamidesSulpirideConceptsNa/H exchanger 3Impact of dopamineNa(+) transportNa-K-ATPase activityResponse to volume expansionProximal tubules in vitroCl(-) reabsorptionPKA-mediated mechanismMicroperfused in vitroEffects of exogenous dopamineMouse proximal tubuleNa-K-ATPaseProximal tubule reabsorptionStimulation of Cl(-PKA inhibitor H89Luminal flowH-ATPase activityTubules in vitroLuminal flow rateNHE3 activityDA1 receptorsNa/H exchangeTubule reabsorptionProximal tubulesInhibitor H89
1990
Cholinergic effect on rat proximal convoluted tubule
Wang T, Chan Y. Cholinergic effect on rat proximal convoluted tubule. Pflügers Archiv - European Journal Of Physiology 1990, 415: 533-539. PMID: 2109302, DOI: 10.1007/bf02583503.Peer-Reviewed Original ResearchConceptsPCT transportProximal convoluted tubulesA-23187Cholinergic receptorsHigher doses of carbacholInhibitory effect of carbacholRate of bicarbonate absorptionConvoluted tubulesCholinergic effectsRegulation of renal functionRat proximal convoluted tubuleEffects of cholinergic agentsEffect of carbacholAddition of carbacholDose of carbacholFunctional cholinergic receptorsCarbachol-induced effectsProximal tubular absorptionIonophore A-23187Bicarbonate-Ringer solutionInhibitory effectNo effectRenal functionBasolateral sideCalcium influx