2011
Differential regulation of ROMK (Kir1.1) in distal nephron segments by dietary potassium
Wade JB, Fang L, Coleman RA, Liu J, Grimm PR, Wang T, Welling PA. Differential regulation of ROMK (Kir1.1) in distal nephron segments by dietary potassium. American Journal Of Physiology. Renal Physiology 2011, 300: f1385-f1393. PMID: 21454252, PMCID: PMC3119145, DOI: 10.1152/ajprenal.00592.2010.Peer-Reviewed Original ResearchConceptsDistal nephronDistal nephron segmentsRenal K secretionROMK knockout miceDietary potassiumExtent of expressionKnockout miceK secretionROMK expressionNephron segmentsNew antibodiesApical labelingPhysiological stimuliNephronROMKAntibodiesROMK channelsApical expressionChannel localizationChannel functionDifferential regulationLarge increaseDCT2Different regulatory mechanismsExtensive pattern
1998
Effect of metabolic acidosis on NaCl transport in the proximal tubule
Wang T, Egbert A, Aronson P, Giebisch G. Effect of metabolic acidosis on NaCl transport in the proximal tubule. American Journal Of Physiology 1998, 274: f1015-f1019. PMID: 9841491, DOI: 10.1152/ajprenal.1998.274.6.f1015.Peer-Reviewed Original ResearchConceptsMetabolic acidosisProximal tubulesNaCl reabsorptionRat proximal tubule segmentsAcidotic ratsNaCl transportNaCl absorptionLate proximal tubuleProximal tubule segmentsControl ratsCapillary perfusateBicarbonate absorptionNephron segmentsAcidosisTubule segmentsRatsRecent evidenceJclTubulesFormate exchangeReabsorptionDifferential regulation