2023
Autism spectrum disorder-specific changes in white matter connectome edge density based on functionally defined nodes
Weber C, Lake E, Haider S, Mozayan A, Bobba P, Mukherjee P, Scheinost D, Constable R, Ment L, Payabvash S. Autism spectrum disorder-specific changes in white matter connectome edge density based on functionally defined nodes. Frontiers In Neuroscience 2023, 17: 1285396. PMID: 38075286, PMCID: PMC10702224, DOI: 10.3389/fnins.2023.1285396.Peer-Reviewed Original ResearchWhite matterPositive symptom correlationAutism spectrum disorderSymptom severity scoresBetween-group differencesAbnormal connectivity patternsCortical nodesVoxel-wise analysisDiffusion tensor imagingSeverity scoreWM fiber tractsSymptom correlationClinical dataConnectome disruptionConnectome changesEarly changesCortical regionsInfantsED reductionWM disruptionDisorder-specific changesTensor imagingFunctional imagingFiber tractsProbabilistic tractography
2020
Behavioral and brain signatures of substance use vulnerability in childhood
Rapuano KM, Rosenberg MD, Maza MT, Dennis NJ, Dorji M, Greene AS, Horien C, Scheinost D, Constable R, Casey BJ. Behavioral and brain signatures of substance use vulnerability in childhood. Developmental Cognitive Neuroscience 2020, 46: 100878. PMID: 33181393, PMCID: PMC7662869, DOI: 10.1016/j.dcn.2020.100878.Peer-Reviewed Original ResearchConceptsConnectome-based predictive modelingSubstance useFunctional connectivityCognitive Development StudyFuture substance useSubstance use vulnerabilityAdolescent substance useSubstance use increasesSubstance use outcomesIndividual differencesAdolescent brainBrain signaturesTask conditionsBehavioral measuresFamilial risk factorsUse outcomesRisky behaviorsLatent dimensionsFamilial factorsBrain modelCurrent studyWeak predictorDevelopment studiesEarly susceptibilityFunctional imaging
2007
Applications and limitations of whole‐brain MAGIC VASO functional imaging
Scouten A, Constable R. Applications and limitations of whole‐brain MAGIC VASO functional imaging. Magnetic Resonance In Medicine 2007, 58: 306-315. PMID: 17654574, PMCID: PMC2673534, DOI: 10.1002/mrm.21273.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingCerebrospinal fluidBlood Oxygenation Level Dependent (BOLD) imagesAuditory stimulationWhole-brain functional magnetic resonance imagingActivation-induced decreaseCerebral blood volumeMagnetic resonance imagingSuperior temporal gyrusBlood volumeThree-compartment modelResonance imagingCSF contributionTemporal gyrusFunctional imagingVisual stimulation