2023
Autism spectrum disorder-specific changes in white matter connectome edge density based on functionally defined nodes
Weber C, Lake E, Haider S, Mozayan A, Bobba P, Mukherjee P, Scheinost D, Constable R, Ment L, Payabvash S. Autism spectrum disorder-specific changes in white matter connectome edge density based on functionally defined nodes. Frontiers In Neuroscience 2023, 17: 1285396. PMID: 38075286, PMCID: PMC10702224, DOI: 10.3389/fnins.2023.1285396.Peer-Reviewed Original ResearchWhite matterPositive symptom correlationAutism spectrum disorderSymptom severity scoresBetween-group differencesAbnormal connectivity patternsCortical nodesVoxel-wise analysisDiffusion tensor imagingSeverity scoreWM fiber tractsSymptom correlationClinical dataConnectome disruptionConnectome changesEarly changesCortical regionsInfantsED reductionWM disruptionDisorder-specific changesTensor imagingFunctional imagingFiber tractsProbabilistic tractography
2008
Additive effects of serotonin transporter and tryptophan hydroxylase-2 gene variation on neural correlates of affective processing
Canli T, Congdon E, Constable R, Lesch K. Additive effects of serotonin transporter and tryptophan hydroxylase-2 gene variation on neural correlates of affective processing. Biological Psychology 2008, 79: 118-125. PMID: 18314252, DOI: 10.1016/j.biopsycho.2008.01.004.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingEvent-related potentialsNeutral facial expressionsSpecific neural lociWord stimuliEmotional scenesAffective processingAffective stimuliEmotional stimuliVerbal stimuliNeural correlatesIndividual differencesNeural processingNeural locusBrain responsesFacial expressionsConvergent evidenceIndependent study samplesFMRI dataRobust effectCortical regionsStimuliTPH2 genotypeTryptophan hydroxylase 2 geneCurrent study
2005
Spatial resolution, signal-to-noise ratio, and smoothing in multi-subject functional MRI studies
Scouten A, Papademetris X, Constable R. Spatial resolution, signal-to-noise ratio, and smoothing in multi-subject functional MRI studies. NeuroImage 2005, 30: 787-793. PMID: 16343951, DOI: 10.1016/j.neuroimage.2005.10.022.Peer-Reviewed Original ResearchConceptsSingle-subject studySpecific cortical regionsFunctional MRI studyBasic neuroscience studiesRandom effects analysisNeurosurgical interventionHemodynamic responseMRI studiesCortical activityCortical regionsFunctional MRIBrain functionFunctional anatomyNeurosurgical planningFunctional mappingSubtle activationClinical environmentGroup-level statisticsNeurophysiological underpinningsPartial volume effectsActivationNeuroscience studiesPatientsGroup statistics
1997
Predicting Reading Performance From Neuroimaging Profiles: The Cerebral Basis of Phonological Effects in Printed Word Identification
Pugh K, Shaywitz B, Shaywitz S, Shankweiler D, Katz L, Fletcher J, Skudlarski P, Fulbright R, Constable R, Bronen R, Lacadie C, Gore J. Predicting Reading Performance From Neuroimaging Profiles: The Cerebral Basis of Phonological Effects in Printed Word Identification. Journal Of Experimental Psychology Human Perception & Performance 1997, 23: 299-318. PMID: 9103996, DOI: 10.1037/0096-1523.23.2.299.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingPhonological effectsLexical decision taskLexical decision latenciesLexical-semantic processesBrain activation patternsWord identificationWord recognitionDecision taskDecision latenciesRegularity effectIndividual differencesFMRI measuresHemispheric lateralizationCerebral basisExperimental paradigmActivation patternsCortical regionsLength effectYoung adultsTaskParticipantsReadingMeasuresMagnetic resonance imaging