2022
Oral Mucosal Sparing in High-Dose Total Body Irradiation (TBI) prior to Stem Cell Transplantation (SCT) for Acute Leukemia
Liveringhouse C, Sandoval M, Dohm A, Weygand J, Garcia G, Peters J, Nieder M, Faramand R, Jain M, Locke F, Bejanyan N, Kim S, Robinson T, Latifi K. Oral Mucosal Sparing in High-Dose Total Body Irradiation (TBI) prior to Stem Cell Transplantation (SCT) for Acute Leukemia. International Journal Of Radiation Oncology • Biology • Physics 2022, 114: e353. DOI: 10.1016/j.ijrobp.2022.07.1462.Peer-Reviewed Original ResearchNon-relapse mortalityTotal body irradiationStem cell transplantationHigh-grade oral mucositisPlanning target volumeOral mucositisAcute oral mucositisAcute lymphocytic leukemiaAcute leukemiaMucosal sparingOral mucosaExact testRisk of NRMHigh-dose total body irradiationDose total body irradiationHost disease (GVHD) prophylaxisResults 25 patientsMedian patient ageSevere oral mucositisFatal respiratory failureFisher's exact testNon-significant trendIMRT/VMATConditioning chemotherapyFatal GVHD
2021
Dosimetric Comparison of Volumetric Modulated Arc Therapy with Tomotherapy Based Total Body Irradiation for Patients Undergoing Conditioning Prior to Hematopoietic Stem Cell Transplantation for Acute Lymphocytic Leukemia
Liveringhouse C, Robinson T, Garcia G, Peters J, Kim S, Latifi K. Dosimetric Comparison of Volumetric Modulated Arc Therapy with Tomotherapy Based Total Body Irradiation for Patients Undergoing Conditioning Prior to Hematopoietic Stem Cell Transplantation for Acute Lymphocytic Leukemia. International Journal Of Radiation Oncology • Biology • Physics 2021, 111: e303. DOI: 10.1016/j.ijrobp.2021.07.950.Peer-Reviewed Original ResearchHematopoietic stem cell transplantationTotal body irradiationAcute lymphocytic leukemiaStem cell transplantationPulmonary toxicityVMAT patientsBody irradiationSixteen patientsCell transplantationLung doseLymphocytic leukemiaHigh-dose total body irradiationAcute grade 3 diarrheaDose total body irradiationThermoplastic immobilizationVMAT plansGrade 3 diarrheaGrade 4 mucositisMean heart doseMean kidney doseResults Sixteen patientsAcute grade 3Common adverse eventsMean lung doseLate pulmonary toxicity