2023
Feasibility and Toxicity of Full-Body Volumetric Modulated Arc Therapy Technique for High-Dose Total Body Irradiation
Keit E, Liveringhouse C, Figura N, Weygand J, Sandoval M, Garcia G, Peters J, Nieder M, Faramand R, Khimani F, Kim S, Robinson T, Johnstone P, Penagaricano J, Latifi K. Feasibility and Toxicity of Full-Body Volumetric Modulated Arc Therapy Technique for High-Dose Total Body Irradiation. Technology In Cancer Research & Treatment 2023, 22: 15330338231180779. PMID: 37287260, PMCID: PMC10272663, DOI: 10.1177/15330338231180779.Peer-Reviewed Original ResearchConceptsHigh-dose total body irradiationTotal body irradiationHelical tomotherapyBody irradiationDosimetric outcomesLower lung dosesMucosal sparing techniquesArc therapy (VMAT) techniqueMucosal sparingHead-first positionMyeloablative conditioningDaily fractionsLung dosesAcute leukemiaPrescription doseHT plansDose goalsFFS plansOAR sparingPatientsLow dosesArc therapyUnique protocolDosesVMAT plans
2021
Dosimetric Comparison of Volumetric Modulated Arc Therapy with Tomotherapy Based Total Body Irradiation for Patients Undergoing Conditioning Prior to Hematopoietic Stem Cell Transplantation for Acute Lymphocytic Leukemia
Liveringhouse C, Robinson T, Garcia G, Peters J, Kim S, Latifi K. Dosimetric Comparison of Volumetric Modulated Arc Therapy with Tomotherapy Based Total Body Irradiation for Patients Undergoing Conditioning Prior to Hematopoietic Stem Cell Transplantation for Acute Lymphocytic Leukemia. International Journal Of Radiation Oncology • Biology • Physics 2021, 111: e303. DOI: 10.1016/j.ijrobp.2021.07.950.Peer-Reviewed Original ResearchHematopoietic stem cell transplantationTotal body irradiationAcute lymphocytic leukemiaStem cell transplantationPulmonary toxicityVMAT patientsBody irradiationSixteen patientsCell transplantationLung doseLymphocytic leukemiaHigh-dose total body irradiationAcute grade 3 diarrheaDose total body irradiationThermoplastic immobilizationVMAT plansGrade 3 diarrheaGrade 4 mucositisMean heart doseMean kidney doseResults Sixteen patientsAcute grade 3Common adverse eventsMean lung doseLate pulmonary toxicity