2024
Quantitative Accuracy Assessment of the NeuroEXPLORER for Diverse Imaging Applications: Moving Beyond Standard Evaluations.
Omidvari N, Shanina E, Leung E, Sun X, Li Y, Mulnix T, Gravel P, Henry S, Matuskey D, Volpi T, Jones T, Badawi R, Li H, Carson R, Qi J, Cherry S. Quantitative Accuracy Assessment of the NeuroEXPLORER for Diverse Imaging Applications: Moving Beyond Standard Evaluations. Journal Of Nuclear Medicine 2024, jnumed.124.268309. PMID: 39638433, DOI: 10.2967/jnumed.124.268309.Peer-Reviewed Original ResearchContrast recovery coefficientHoffman phantomUniform phantomIQ phantomRecovery coefficientBrain PET systemHoffman brain phantomBrain uptakeSpatial resolutionDiverse imaging applicationsCylindrical phantomPET systemBrain phantomNeuroimaging studiesImage qualityImaging conditionsPhantomReconstruction parametersImaging time pointsTime pointsImage-derived input functionHigher spatial resolutionQuantitative accuracyDelayed time pointsBrain disordersPerformance Characteristics of the NeuroEXPLORER, a Next-Generation Human Brain PET/CT Imager
Li H, Badawi R, Cherry S, Fontaine K, He L, Henry S, Hillmer A, Hu L, Khattar N, Leung E, Li T, Li Y, Liu C, Liu P, Lu Z, Majewski S, Matuskey D, Morris E, Mulnix T, Omidvari N, Samanta S, Selfridge A, Sun X, Toyonaga T, Volpi T, Zeng T, Jones T, Qi J, Carson R. Performance Characteristics of the NeuroEXPLORER, a Next-Generation Human Brain PET/CT Imager. Journal Of Nuclear Medicine 2024, 65: jnumed.124.267767. PMID: 38871391, PMCID: PMC11294061, DOI: 10.2967/jnumed.124.267767.Peer-Reviewed Original ResearchPeak noise-equivalent count rateNoise-equivalent count rateTime-of-flight resolutionField of viewCount rateExtended axial field-of-viewTransverse field-of-viewAxial field-of-viewField-of-view centerMini-Derenzo phantomSpatial resolutionTangential spatial resolutionsCount rate performanceContrast recovery coefficientHuman brain PET imagingMeasurements of spatial resolutionNEMA sensitivityEnergy resolutionScatter fractionBrain phantomBackprojection reconstructionBrain PET imagingTime resolutionRadial offsetF-FDG imagingRelationship between neuroimaging and cognition in frontotemporal dementia: An FDG‐PET and structural MRI study
Cayir S, Volpi T, Toyonaga T, Gallezot J, Yang Y, Sadabad F, Mulnix T, Mecca A, Fesharaki‐Zadeh A, Matuskey D. Relationship between neuroimaging and cognition in frontotemporal dementia: An FDG‐PET and structural MRI study. Journal Of Neuroimaging 2024, 34: 627-634. PMID: 38676301, PMCID: PMC11511789, DOI: 10.1111/jon.13206.Peer-Reviewed Original ResearchMoCA scoresFDG-PETAssociation of cognitionStandardized uptake value ratioMontreal Cognitive AssessmentSignificant positive associationFrontotemporal dementiaPrimary outcome measurePosterior cingulate cortexDecline of cognitive functionYears of ageGM volumeFrontal cortexOutcome measuresCognitive dysfunctionGray matterCognitive AssessmentMoCAAssociated with cognitive dysfunctionFluorodeoxyglucose (FDG)-PETPositive associationMagnetic resonance imagingPartial volume correctionCognitive functionDementia
2022
Event-by-Event 3D Continuous Motion Correction Based on a Data-Driven Motion Estimation Algorithm for 82Rb Myocardial Perfusion Imaging
Tsai Y, Fontaine K, Mulnix T, Armstrong I, Hayden C, Spottiswoode B, Casey M, Liu C. Event-by-Event 3D Continuous Motion Correction Based on a Data-Driven Motion Estimation Algorithm for 82Rb Myocardial Perfusion Imaging. 2022, 00: 1-4. DOI: 10.1109/nss/mic44845.2022.10399100.Peer-Reviewed Original ResearchMotion correctionData-driven motion estimationPET/CT scannerSuperior-inferior motionMotion effectsSilicon photomultipliersNEMA phantomReconstruction frameworkPET acquisitionReconstructed image qualityCardiac PETMotion estimation algorithmPatient datasetsImage qualityMyocardial perfusion imagingCorrectionMotion monitoringTemporal resolutionSiPMMotionPhotomultiplierMotion estimationMotion vectorsPhantomCorrection algorithm