2024
ACE Inhibitor Use Does Not Significantly Affect Occurrence of Manipulation Under Anesthesia Following Total Knee Arthroplasty
Frederick J, Gazgalis A, Peterson J, Hickernell T, Cooper H, Shah R, Geller J, Neuwirth A. ACE Inhibitor Use Does Not Significantly Affect Occurrence of Manipulation Under Anesthesia Following Total Knee Arthroplasty. Journal Of Orthopaedic Experience & Innovation 2024, 5 DOI: 10.60118/001c.89993.Peer-Reviewed Original ResearchAngiotensin-converting enzyme inhibitorsAngiotensin converting enzyme inhibitor medicationRange of motionPost-operative stiffnessTotal knee arthroplastyAmerican Society of Anesthesiologists classACE inhibitor useConverting enzyme inhibitorsStudent's t-testAttenuated fibroblast proliferationKnee arthroplastyChi-square testScar tissue formationInhibitor useNo significant differenceCohort patientsChart reviewControl patientsPost-operativelyFollow-upControl cohortCommon medicationsOdds ratioPatientsEnzyme inhibitors
2022
Perioperative Intravenous Glucocorticoids in Total Joint Arthroplasty: A Systematic Review
Ruberto R, Farah O, Lopez C, Hickernell T. Perioperative Intravenous Glucocorticoids in Total Joint Arthroplasty: A Systematic Review. Journal Of The American Academy Of Orthopaedic Surgeons 2022, 31: e94-e106. PMID: 36580055, DOI: 10.5435/jaaos-d-22-00232.Peer-Reviewed Original ResearchConceptsTotal joint arthroplastyPostoperative surgical complicationsPostoperative painSystematic reviewPerioperative glucocorticoidsPerioperative steroidsPostoperative nauseaSurgical complicationsGlucocorticoid administrationJoint arthroplastyMultimodal pain controlPerioperative glucocorticoid administrationPerioperative steroid administrationPostoperative opioid utilizationRescue medication useAdditional randomized trialsCommon orthopaedic proceduresNotable adverse effectsRange of motionIntravenous glucocorticoidsHospital lengthOpioid utilizationPain controlPain scoresPostoperative length