2019
Whole Genome CRISPR-Cas9 Screen Identifies STING as a Determinant of Intrinsic Radiosensitivity in Head and Neck Squamous Cell Carcinoma
Hayman T, Baro M, Cui W, Contessa J. Whole Genome CRISPR-Cas9 Screen Identifies STING as a Determinant of Intrinsic Radiosensitivity in Head and Neck Squamous Cell Carcinoma. International Journal Of Radiation Oncology • Biology • Physics 2019, 105: s77-s78. DOI: 10.1016/j.ijrobp.2019.06.538.Peer-Reviewed Original Research
2018
CDKN2A Copy Number Loss Is an Independent Prognostic Factor in HPV-Negative Head and Neck Squamous Cell Carcinoma
Chen WS, Bindra RS, Mo A, Hayman T, Husain Z, Contessa JN, Gaffney SG, Townsend JP, Yu JB. CDKN2A Copy Number Loss Is an Independent Prognostic Factor in HPV-Negative Head and Neck Squamous Cell Carcinoma. Frontiers In Oncology 2018, 8: 95. PMID: 29670856, PMCID: PMC5893829, DOI: 10.3389/fonc.2018.00095.Peer-Reviewed Original ResearchDisease-free survivalNeck squamous cell carcinomaSquamous cell carcinomaOverall survivalHPV-negative HNSCCPrognostic factorsCell carcinomaPoor survivalLoss groupCDKN2A mRNAMedian disease-free survivalP16 expressionCopy number lossNumber lossMedian overall survivalReceipt of chemotherapyIndependent prognostic factorUseful prognostic factorHPV-negative headHigh p16 expressionProtein expression levelsHPV infectionCancer Genome AtlasBetter prognosisMultivariable analysis