2020
A Randomized Trial of a Multifactorial Strategy to Prevent Serious Fall Injuries
Bhasin S, Gill TM, Reuben DB, Latham NK, Ganz DA, Greene EJ, Dziura J, Basaria S, Gurwitz JH, Dykes PC, McMahon S, Storer TW, Gazarian P, Miller ME, Travison TG, Esserman D, Carnie MB, Goehring L, Fagan M, Greenspan SL, Alexander N, Wiggins J, Ko F, Siu AL, Volpi E, Wu AW, Rich J, Waring SC, Wallace RB, Casteel C, Resnick NM, Magaziner J, Charpentier P, Lu C, Araujo K, Rajeevan H, Meng C, Allore H, Brawley BF, Eder R, McGloin JM, Skokos EA, Duncan PW, Baker D, Boult C, Correa-de-Araujo R, Peduzzi P. A Randomized Trial of a Multifactorial Strategy to Prevent Serious Fall Injuries. New England Journal Of Medicine 2020, 383: 129-140. PMID: 32640131, PMCID: PMC7421468, DOI: 10.1056/nejmoa2002183.Peer-Reviewed Original ResearchConceptsSerious fall injuriesFall injuriesIntervention groupControl groupUsual careMultifactorial interventionRate of hospitalizationPrimary care practicesCluster-randomized trialCommunity-dwelling adultsFirst-event analysisYears of ageHealth care systemRate of fallElectronic health recordsBaseline characteristicsPrimary outcomeRandomized trialsMean ageEfficacy trialsIndividualized planCare practicesInjuryMultifactorial strategyEvent rates
2017
Serious adverse events of older adults in nursing home and community intervention trials
Datta R, Trentalange M, Van Ness PH, McGloin JM, Guralnik JM, Miller ME, Walkup MP, Nadkarni N, Pahor M, Gill TM, Quagliarello V, Juthani-Mehta M, Group F. Serious adverse events of older adults in nursing home and community intervention trials. Contemporary Clinical Trials Communications 2017, 9: 77-80. PMID: 29696228, PMCID: PMC5898490, DOI: 10.1016/j.conctc.2017.12.004.Peer-Reviewed Original ResearchUnanticipated serious adverse eventsSerious adverse eventsNursing home residentsTotal serious adverse eventsHome residentsSAE incidenceAdverse eventsClinical trialsOlder adultsCommunity dwellersNursing homesIncidence of SAEsFemale nursing home residentsProportion of patientsRandomized clinical trialsCommunity intervention trialStructured physical activityCranberry capsulesLifestyle interventionRandomized trialsIntervention trialsElders StudyHealth centersSecondary data analysisPhysical activity
2016
Effect of Structured Physical Activity on Overall Burden and Transitions Between States of Major Mobility Disability in Older Persons: Secondary Analysis of a Randomized Trial.
Gill TM, Guralnik JM, Pahor M, Church T, Fielding RA, King AC, Marsh AP, Newman AB, Pellegrini CA, Chen SH, Allore HG, Miller ME. Effect of Structured Physical Activity on Overall Burden and Transitions Between States of Major Mobility Disability in Older Persons: Secondary Analysis of a Randomized Trial. Annals Of Internal Medicine 2016, 165: 833-840. PMID: 27669457, PMCID: PMC5476905, DOI: 10.7326/m16-0529.Peer-Reviewed Original ResearchConceptsMajor mobility disabilityStructured physical activity programPhysical activity programPhysical activityMobility disabilityHealth educationActivity programStructured physical activityHealth education interventionNational InstituteOnset of disabilityQuality of lifeDisability episodeTreat principleRandomized trialsPatient assessmentRisk ratioOverall burdenProportion of assessmentsSedentary personsFunctional limitationsU.S. CentersEnhanced recoverySecondary analysisOlder persons