2019
Impact of Baseline Fatigue on a Physical Activity Intervention to Prevent Mobility Disability
Glynn N, Gmelin T, Santanasto A, Lovato L, Lange‐Maia B, Nicklas B, Fielding R, Manini T, Myers V, Rekeneire N, Spring B, Pahor M, King A, Rejeski W, Newman A, Pahor M, Guralnik J, Anton S, Buford T, Leeuwenburgh C, Nayfield S, Manini T, Caudle C, Crump L, Holmes L, Lee J, Lu C, Miller M, Espeland M, Ambrosius W, Applegate W, Beavers D, Byington R, Cook D, Furberg C, Harvin L, Henkin L, Hepler J, Hsu F, Joyce K, Lovato L, Pierce J, Roberson W, Robertson J, Rushing J, Rushing S, Stowe C, Walkup M, Hire D, Rejeski W, Katula J, Brubaker P, Mihalko S, Jennings J, Chen S, Pierce J, Chen H, Hadley E, Romashkan S, Patel K, Bethesda, Bonds D, McDermott M, Spring B, Hauser J, Kerwin D, Domanchuk K, Graff R, Rego A, Church T, Blair S, Myers V, Monce R, Britt N, Harris M, McGucken A, Rodarte R, Millet H, Tudor‐Locke C, Butitta B, Donatto S, Cocreham S, King A, Castro C, Haskell W, Stafford R, Pruitt L, Yank V, Berra K, Bell C, Thiessen R, Youngman K, Virgen S, Maldonado E, Tarin K, Klaftenegger H, Prosak C, Campero I, Garcia D, Soto J, Chio L, Hoskins D, Fielding R, Nelson M, Folta S, Phillips E, Liu C, McDavitt E, Reid K, Kirn D, Pasha E, Kim W, Krol J, Beard V, Tsiroyannis E, Hau C, Manini T, Pahor M, Anton S, Buford T, Marsiske M, Nayfield S, Sandesara B, Black M, Burk W, Hoover B, Knaggs J, Marena W, Korytov I, Curtis S, Lorow M, Goswami C, Lewis M, Kamen M, Bitz J, Stanton B, Hicks T, Gay C, Xie C, Morris H, Singletary F, Causer J, Yonce S, Radcliff K, Smith M, Scott J, Rodriguez M, Fitch M, Dunn M, Schllesinger J, Newman A, Studenski S, Goodpaster B, Lopez O, Glynn N, Nadkarni N, Ives D, Newman M, Grove G, Williams K, Bonk J, Rush J, Kost P, Vincent P, Gerger A, Romeo J, Monheim L, Kritchevsky S, Marsh A, Brinkley T, Demons J, Sink K, Kennedy K, Shertzer‐Skinner R, Wrights A, Fries R, Barr D, Gill T, Axtell R, Kashaf S, Rekeneire N, McGloin J, Mautner R, Huie‐White S, Bianco L, Zocher J, Wu K, Shepard D, Fennelly B, Castro R, Halpin S, Brennan M, Barnett T, Iannone L, Zenoni M, Bugaj J, Bailey C, Charpentier P, Hawthorne‐Jones G, Mignosa B, Lewis L, Williamson J, Sink K, Hendrie H, Rapp S, Verghese J, Woolard N, Espeland M, Jennings J, Wilson V, Pepine C, Ariet M, Handberg E, Deluca D, Hill J, Szady A, Chupp G, Flynn G, Gill T, Hankinson J, Vaz Fragoso C, Groessl E, Kaplan R. Impact of Baseline Fatigue on a Physical Activity Intervention to Prevent Mobility Disability. Journal Of The American Geriatrics Society 2019, 68: 619-624. PMID: 31867713, PMCID: PMC8061638, DOI: 10.1111/jgs.16274.Peer-Reviewed Original ResearchConceptsPersistent major mobility disabilityMajor mobility disabilityStructured PA interventionPhysical activity interventionsBaseline fatiguePA interventionsMobility disabilityActivity interventionsRisk of MMDHealth educationIncident major mobility disabilityModerate-intensity PA interventionHigher baseline fatigueProportional hazards modelSelf-reported fatigueYears of ageLifestyle interventionProspective cohortElders StudyHazards modelLower riskStudy participantsMore fatigueLess fatiguePast weekRATINGS OF PERCEIVED EXERTION: PREDICTING MOBILITY DISABILITY AND RESPONSE TO PHYSICAL ACTIVITY IN OLDER ADULTS
Cenko E, Gill T, Glynn N, Pahor M, Qiu P, Valiani V, You L, Manini T. RATINGS OF PERCEIVED EXERTION: PREDICTING MOBILITY DISABILITY AND RESPONSE TO PHYSICAL ACTIVITY IN OLDER ADULTS. Innovation In Aging 2019, 3: s969-s969. PMCID: PMC6845125, DOI: 10.1093/geroni/igz038.3512.Peer-Reviewed Original ResearchMajor mobility disabilityOlder adultsHE groupPA groupMobility disabilityRisk of MMDIncident major mobility disabilityPhysical activity programHealth education programsStructured PA programStructured PAWalk testHigh riskActivity programPerceived ExertionPA programsRPEMobility impairmentsAdultsExertionRiskDisabilityGroupPhysiological indicesParticipants
2016
Effect of Structured Physical Activity on Overall Burden and Transitions Between States of Major Mobility Disability in Older Persons: Secondary Analysis of a Randomized Trial.
Gill TM, Guralnik JM, Pahor M, Church T, Fielding RA, King AC, Marsh AP, Newman AB, Pellegrini CA, Chen SH, Allore HG, Miller ME. Effect of Structured Physical Activity on Overall Burden and Transitions Between States of Major Mobility Disability in Older Persons: Secondary Analysis of a Randomized Trial. Annals Of Internal Medicine 2016, 165: 833-840. PMID: 27669457, PMCID: PMC5476905, DOI: 10.7326/m16-0529.Peer-Reviewed Original ResearchConceptsMajor mobility disabilityStructured physical activity programPhysical activity programPhysical activityMobility disabilityHealth educationActivity programStructured physical activityHealth education interventionNational InstituteOnset of disabilityQuality of lifeDisability episodeTreat principleRandomized trialsPatient assessmentRisk ratioOverall burdenProportion of assessmentsSedentary personsFunctional limitationsU.S. CentersEnhanced recoverySecondary analysisOlder persons
2014
Effect of Structured Physical Activity on Prevention of Major Mobility Disability in Older Adults: The LIFE Study Randomized Clinical Trial
Pahor M, Guralnik JM, Ambrosius WT, Blair S, Bonds DE, Church TS, Espeland MA, Fielding RA, Gill TM, Groessl EJ, King AC, Kritchevsky SB, Manini TM, McDermott MM, Miller ME, Newman AB, Rejeski WJ, Sink KM, Williamson JD. Effect of Structured Physical Activity on Prevention of Major Mobility Disability in Older Adults: The LIFE Study Randomized Clinical Trial. JAMA 2014, 311: 2387-2396. PMID: 24866862, PMCID: PMC4266388, DOI: 10.1001/jama.2014.5616.Peer-Reviewed Original ResearchConceptsMajor mobility disabilityPhysical activity groupModerate-intensity physical activity programHealth education groupPhysical activity programHealth education programsMobility disabilityOlder adultsActivity programClinical trialsActivity groupPhysical activityIncident major mobility disabilityShort Physical Performance BatteryPersistent mobility disabilityPhysical activity preventsEducation groupSerious adverse eventsIndependent risk factorPhysical Performance BatteryDefinitive clinical trialsStructured physical activityVulnerable older adultsAdverse eventsLifestyle intervention
2012
Risk factors and precipitants of long-term disability in community mobility: a cohort study of older persons.
Gill TM, Gahbauer EA, Murphy TE, Han L, Allore HG. Risk factors and precipitants of long-term disability in community mobility: a cohort study of older persons. Annals Of Internal Medicine 2012, 156: 131-40. PMID: 22250144, PMCID: PMC3278794, DOI: 10.7326/0003-4819-156-2-201201170-00009.Peer-Reviewed Original ResearchConceptsLong-term disabilityRisk factorsOlder personsCohort studyCommunity mobilityShort Physical Performance BatteryMultivariate hazard ratiosProspective cohort studyPhysical Performance BatteryMultiple risk factorsCandidate risk factorsSpecific risk factorsNational InstituteLong-term mobility disabilityHazard ratioAbsolute riskPerformance BatteryPotential precipitantsMobility disabilityRestricted activityOlder ageObserved associationsInitial onsetStrong associationQuarter mile
2006
Effects of a Physical Activity Intervention on Measures of Physical Performance: Results of the Lifestyle Interventions and Independence for Elders Pilot (LIFE-P) Study
Pahor M, Blair S, Espeland M, Fielding R, Gill T, Guralnik J, Hadley E, King A, Kritchevsky S, Maraldi C, Miller M, Newman A, Rejeski W, Romashkan S, Studenski S. Effects of a Physical Activity Intervention on Measures of Physical Performance: Results of the Lifestyle Interventions and Independence for Elders Pilot (LIFE-P) Study. The Journals Of Gerontology Series A 2006, 61: 1157-1165. PMID: 17167156, DOI: 10.1093/gerona/61.11.1157.Peer-Reviewed Original ResearchConceptsShort Physical Performance BatteryPhysical activity interventionsSPPB scoreMobility disabilityActivity interventionsPA interventionsPA groupBaseline short physical performance batteryComprehensive physical activity interventionModerate-intensity PA interventionElders Pilot StudyStructured PA interventionPhysical performanceDaily living (ADL) disabilityMajor mobility disabilityPhysical Performance BatteryHealth education interventionPhysical performance measuresDistal health outcomesLifestyle interventionSPPB performanceMore distal health outcomesLower incidenceSedentary personsPerformance Battery