2020
Empiric Recurrence Risk Estimates for Chronic Tic Disorders: Implications for Genetic Counseling
Heiman GA, Rispoli J, Seymour C, Leckman JF, King RA, Fernandez TV. Empiric Recurrence Risk Estimates for Chronic Tic Disorders: Implications for Genetic Counseling. Frontiers In Neurology 2020, 11: 770. PMID: 32849224, PMCID: PMC7432137, DOI: 10.3389/fneur.2020.00770.Peer-Reviewed Original ResearchChronic tic disorderRecurrence risk estimatesTic disordersRecurrence riskTourette's disorderRisk estimatesNeuropsychiatric disordersPopulation-based family studyGenetic counselingFirst-degree relativesQuality of lifeFamily studiesVocal ticsPopulation prevalenceFamilial recurrence riskSuch counselingGenetic testingDisordersRiskCounselingEmpiric recurrence riskGenetic variantsRange of risksHeterogeneous genetic architectureComorbidities
2015
Tourette Syndrome: Bridging the Gap between Genetics and Biology
Richer P, Fernandez TV. Tourette Syndrome: Bridging the Gap between Genetics and Biology. Complex Psychiatry 2015, 1: 156-164. PMID: 26509143, PMCID: PMC4617782, DOI: 10.1159/000439085.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsGenetic studiesNeuropsychiatric disordersGenetic complexityInvolvement of dopaminergicPrecise therapeutic targetsChildhood neuropsychiatric disordersAttention deficit hyperactivity disorderGenetic overlapGenetic alterationsBiologyDeficit hyperactivity disorderHistaminergic pathwayObsessive-compulsive disorderHigh comorbidityVocal ticsCurrent treatmentTherapeutic targetTourette syndromePhenotypeHyperactivity disorderImproved treatmentDisordersDiseaseTreatmentGenetics