2023
Correlation of a commercial platform’s results with post-vaccination SARS-CoV-2 neutralizing antibody response and clinical host factors
Slotkin R, Kyriakides T, Kundu A, Stack G, Sutton R, Gupta S. Correlation of a commercial platform’s results with post-vaccination SARS-CoV-2 neutralizing antibody response and clinical host factors. PLOS ONE 2023, 18: e0289713. PMID: 37643190, PMCID: PMC10464955, DOI: 10.1371/journal.pone.0289713.Peer-Reviewed Original ResearchBaseline Features and Reasons for Nonparticipation in the Colonoscopy Versus Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM) Study, a Colorectal Cancer Screening Trial
Robertson D, Dominitz J, Beed A, Boardman K, Del Curto B, Guarino P, Imperiale T, LaCasse A, Larson M, Gupta S, Lieberman D, Planeta B, Shaukat A, Sultan S, Menees S, Saini S, Schoenfeld P, Goebel S, von Rosenvinge E, Baffy G, Halasz I, Pedrosa M, Kahng L, Cassim R, Greer K, Kinnard M, Bhatt D, Dunbar K, Harford W, Mengshol J, Olson J, Patel S, Antaki F, Fisher D, Sullivan B, Lenza C, Prajapati D, Wong H, Beyth R, Lieb J, Manlolo J, Ona F, Cole R, Khalaf N, Kahi C, Kohli D, Rai T, Sharma P, Anastasiou J, Hagedorn C, Fernando R, Jackson C, Jamal M, Lee R, Merchant F, May F, Pisegna J, Omer E, Parajuli D, Said A, Nguyen T, Tombazzi C, Feldman P, Jacob L, Koppelman R, Lehenbauer K, Desai D, Madhoun M, Tierney W, Ho M, Hockman H, Lopez C, Carter Paulson E, Tobi M, Pinillos H, Young M, Ho N, Mascarenhas R, Promrat K, Mutha P, Pandak W, Shah T, Schubert M, Pancotto F, Gawron A, Underwood A, Ho S, Magno-Pagatzaurtundua P, Toro D, Beymer C, Kaz A, Elwing J, Gill J, Goldsmith S, Yao M, Protiva P, Pohl H, Kyriakides T, Kleiner E, Sullivan K, O'Leary J, Chiu W, Huang H, Russo J, Johnson G, Antonelli P, Burns A, Peduzzi P, Ciarleglio M, O'Connor T, Wallace R, Williams A, Tommessilli L, Taylor S, Pitts S, Mancini L, O'Brien P, O'Neil S, Perry M, McBride V, Carr W, Joncas C, O'Donnell E, Sather M, Warren S, Conner T, Honstein E, Sutton T, Putnam T, Branham K, Argyres D, Peterson D, Kennedy A, Carrick T, Apodaca C, Eden G, Martinez T, Tripp C, Nicholson M, Schwartz A, Felix M, Ward A, Marquez L, Lovato K, Cochran N, Tapia S, VanRaden M, Badgett C, Taylor Z, Pontzer J, Dorman B, Chavez M, Georg S, Templton T, Calais L, Haakensen C, Curtis B, Prehoda M, Colling C, Older D, Apodaca G, Sova J, Klee M, Wolfram-Aduan A, Ulatowski M, Hamilton B, Bopp (Formerly England) K, Ford G, Lace N, McDonnell W, Piehl G, Patel-Ejarque N, Berry M, Strubeck E, Chesnut L, Burridge L, Bean J, Kowal L, Voorhees (Formerly Rose) A, Ridley A, Croteau H, Bessett K, Fletcher C, Barbaresso M, Drummond A, Belanger K, McRobert E, Myers A, Trumble E, Rose P, Biswas A, Enache E, Shankin M, Strunk D, Simpson A, Harrison M, Prasad M, Robinson P, Flores A, Jananeh S, Tanukonda S, Ahmadi-Izadi G, Madihi S, Raufman J, Grady D, Britton A, Goldstein C, Thomas M, Lee V, Belizaire M, Costa C, Davis S, Decker M, Marrama A, Gilroy-Fanaras D, Gass J, Reece S, Tobin D, Carroll R, Ferreira M, Irvin D, Morken V, Covelli M, Medina T, Schiebel F, Shreves A, Shriver D, Frederick Y, Postle (formerly Matheny) C, Shaw J, Pastor D, Armstrong A, Kumaran V, Pinto A, Marshall V, McLarty S, Carlton J, Murphy K, McLemore K, Mortensen E, LePage J, Willis C, Berman K, Dunn T, Espinoza J, Schleski E, Shrader S, Gropp K, Kanaan Z, Miller L, Anees M, Judd S, Berchou V, Balogh D, Jones E, Covert K, Davis Y, Marbury C, Rambus M, Olgren E, Gellad Z, Sullivan B, Day T, Teehan S, Peters L, Hernandez-Chavez R, Murphy E, Cherry J, Graham E, Johnson J, Wooten W, Trujillo J, Harris M, Alizadeh M, Lo M, Sultan S, Brown L, Koster L, LeLaurin J, Irwin A, Kay N, Mckillip S, Lowe M, Yeralan S, Leehey D, McBurney C, Jain A, Park T, Broadwater L, El-Serag H, Shaib Y, Taylor E, Nair P, Broussard E, Gibson E, Hawkins R, Natividad T, Courtade D, Palmer M, Martinez S, Panagiotis K, Morrow C, Ballard C, Barker B, Garner M, McCalley S, Schwartzkopf A, Wright A, Titi M, Higbee A, Pratiksha S, Jones A, Shipe T, McKee J, Vennalaganti R, Terrey K, Maruf L, Brown D, Crouse E, Marchant-Miros K, Ussery B, Ducker L, Estell J, Porchia S, Kim M, Kim C, Chan B, Hayton A, Christiansen H, Peterson M, Ding G, Simpson V, Read S, Mamani G, Salazar J, Kato J, Bowie M, Carnevale R, Halim M, Sahagian A, Ibarra A, Travis Z, Garcia J, Gill A, Starzyk J, Sumarli S, Johnson V, Peresuh S, Quimby T, Cordova R, Herold L, Hawley A, Goo T, Kidao J, Lee R, Freidel C, Gutierrez E, Noorisharghi N, Ivie G, Jawish T, Partin S, Yoo G, Fabilane C, Noori N, Lang E, Senen S, Partin S, Fathi M, Chauvin R, Feiger J, Reataza M, Morgan T, Asghar A, Jacobs J, Kashefi M, May F, Ohning G, Padua D, Smutko V, Oh D, Kosoyan H, Dreskin B, Luu K, Alas A, Bharath P, Dixit V, Sanford** D, Vu J, Kadi S, Nwajuaku T, Smith J, Kincaid J, Mir M, Lanceta J, Rice J, Agarwal P, Augustine A, Prickel H, Vue J, Guerrero K, Levenson S, Aguilera-Fish A, Chestnut L, Jobse B, Lombardo C, Silver T, Ahmed N, Bockhold K, Koppelman R, Carneiro F, Garcia-Morales R, Spector D, Gomez J, Lehenbauer K, Reinink A, Anway R, Evans-Lindquist M, Eggers T, Green M, Pretti A, Meyeraan T, Condon D, Cavanagh M, DeFalco C, Cutting J, Joseph K, Dean S, Mitchell S, Phillips V, Krueger C, Zink D, Goldberg K, Patel N, Martinez Gonzalez M, Davis-Underwood H, O'Sullivan A, Suppes T, Bratcher K, Stern D, Wu R, Damisa J, Warsi R, Nguyen T, Pinillos H, Flowers E, Kuramoto A, Thurmond C, Orozco L, Farrell G, Jaynes R, Saenz P, Perez C, Collins J, Lin E, Onstad L, Pitts A, Osborn K, Kenworthy-Heinige T, Casey A, Gold D, Olivo C, Joos S, Subramanian S, Forro V, Cannady A, Usih J, Raitt M, Flynn M, Shittu Y, Jawaid M, Anderson R, Poole D, Butler C, Snead L, Christine H, Swanson G, Heumann D, Pandak W, Spataro J, Bajaj J, Solomon C, Smith Gilles H, Zafass A, Tilak S, Fuchs M, Davis M, Blackman L, Lemler J, Munsey R, Deebo J, McCarthy J, Noel M, Hurley R, Zurowski W, Sharpe A, Wilson K, Peets R, Lorenso B, Burrison S, Johnson D, Angelovic A, Erickson N, Hanson H, Bailey T, Genung K, Dulin H, Neuharth R, Clegg D, Velarde K, Dever J, Murphy M, Beck D, Wasil M, Vazquez J, O'Neil E, Ganji G, Ducom J, Lee M, Hovespians R, Margolis J, Simmons B, Sweeney (formerly St. Martin) J, Henry R, Martin-Ortiz J, Santiago-Rivera L, Gonzalez - Aviles G, Pedrosa C, Bird-Caceres J, Padilla B, Baez-Corujo F, Martinez- Ortiz Y, Vazquez E, Grigg-Gutierrez N, Laboy-Olivieri C, Urbina-Velez R, Andrews S, Rosa-Cruz S, Tirado-Montijo R, Otero-Aponte K, Martinez-Martino M, Freire A, Soto-Ramos A, Santana-Perez M, Araujo J, Vanderwarker C, Alexander J, Nevins E, LaGuire J, Guerrero L, Piehl G, Jenkins M, Chen T, Jang J, Tanus A, McKelvy P, Sayuk G, Chandiramani P, Vargo (Formerly Shoults) L, Vargo K, Lawrence S, Blythe K, Goldsmith S, Campbell R, Craddock M, Amodeo D, Reinhard R, Durant B, Wells B, Zoble A, Papademetriou M, Roche N, Adler P, Krishna A, Glaze D, Wijegunawardana D, Yeroushalmi S, Laine L, Mautner R, Bugaj J, Anderson J, Croteau H, Kingman L, Burridge L. Baseline Features and Reasons for Nonparticipation in the Colonoscopy Versus Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM) Study, a Colorectal Cancer Screening Trial. JAMA Network Open 2023, 6: e2321730. PMID: 37432690, PMCID: PMC10336619, DOI: 10.1001/jamanetworkopen.2023.21730.Peer-Reviewed Original ResearchConceptsFecal immunochemical testImmunochemical testEligible individualsAnnual fecal immunochemical testColorectal Cancer Screening TrialScreening testVeterans Affairs Medical CenterAverage CRC riskCancer Screening TrialCancer mortality outcomesCross-sectional studySpecific screening testCase report formsColorectal Cancer StudyStudy participant characteristicsCross-sectional analysisStool testingCRC riskMortality outcomesColorectal cancerClinical trialsCONFIRM studyMedical CenterScreening preferencesHispanic ethnicityAnalysis of Repair Type and Hypogastric Artery Antegrade Perfusion and Erectile Function following Repair of Abdominal Aortic Aneurysms
Bennett K, Hurley L, Kyriakides T, Matsumura J, Group O. Analysis of Repair Type and Hypogastric Artery Antegrade Perfusion and Erectile Function following Repair of Abdominal Aortic Aneurysms. Annals Of Vascular Surgery 2023, 94: 186-194. PMID: 37164171, DOI: 10.1016/j.avsg.2023.04.025.Peer-Reviewed Original ResearchConceptsErectile functionArtery perfusionErectile dysfunctionHypogastric flowEndovascular repairAneurysm repairAortic aneurysmAntegrade perfusionPreoperative ankle-brachial indexErectile Function-5 (IIEF-5) questionnaireAbdominal aortic aneurysm repairHypogastric artery exclusionSignificant erectile dysfunctionThoracic aortic proceduresAnkle-brachial indexBeta-blocker useFifth of patientsSpinal cord ischemiaAortic aneurysm repairAbdominal aortic aneurysmMixed effects regression modelsBranched deviceButtock claudicationEndovascular groupBlocker use
2022
Clinical and virologic factors associated with outcomes of COVID‐19 before and after vaccination among Veterans: Retrospective analysis from six New England states
Lee M, Cosentino D, Kyriakides TC, Cavallaro T, Stack G, Gupta S. Clinical and virologic factors associated with outcomes of COVID‐19 before and after vaccination among Veterans: Retrospective analysis from six New England states. Journal Of Hospital Medicine 2022, 17: 534-538. PMID: 35661577, PMCID: PMC9348310, DOI: 10.1002/jhm.12852.Peer-Reviewed Original ResearchConceptsCOVID-19Intensive care unit admissionVeterans Administration Healthcare SystemCare unit admissionNonpsychiatric hospitalizationsVirologic factorsFull vaccinationUnit admissionICU careClinical outcomesPoor outcomeMean ageRetrospective analysisD614G mutationHealthcare systemVeteransNew England statesHospitalizationOlder cohortOutcomesViral epidemiologyVaccinationDemographic factorsG mutationAge
2020
Clinic-Based Pediatric Disclosure Intervention Trial Improves Pediatric HIV Status Disclosure in Ghana.
Paintsil E, Kyriakides TC, Antwi S, Renner L, Nichols JS, Amissah K, Kusah JT, Alhassan A, Ofori IP, Catlin AC, Gan G, Lartey M, Reynolds NR. Clinic-Based Pediatric Disclosure Intervention Trial Improves Pediatric HIV Status Disclosure in Ghana. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2020, 84: 122-131. PMID: 32049772, PMCID: PMC7138721, DOI: 10.1097/qai.0000000000002316.Peer-Reviewed Original ResearchConceptsTreatment groupsHIV disclosure interventionsHIV health careHIV-positive childrenMultivariate Cox modelDisclosure interventionHIV status disclosureBetter overall treatment effectHealth care providersYears of ageChild-caregiver dyadsOverall treatment effectModified intentionHIV clinicHIV statusIntervention armIntervention trialsStatus disclosureTreat approachCare providersCox modelTime pointsTherapeutic communicationControl participantsHealth care
2019
Employment Outcomes From VA Vocational Services Involving Transitional Work for Veterans With a Diagnosis of Posttraumatic Stress Disorder
Davis LL, Resnick SG, Maieritsch KP, Weber KC, Erbes CR, Strom TQ, McCall KP, Kyriakides TC. Employment Outcomes From VA Vocational Services Involving Transitional Work for Veterans With a Diagnosis of Posttraumatic Stress Disorder. Psychiatric Rehabilitation Journal 2019, 42: 257-267. PMID: 30945920, PMCID: PMC6910199, DOI: 10.1037/prj0000357.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderVeterans Health AdministrationStress disorderCompetitive employment outcomesStudy of veteransComparative subgroup analysisCompetitive jobsBaseline characteristicsSubgroup analysisHealth AdministrationYounger agePsychiatric disabilitiesTransitional workPotential subgroupsNonengagersOutcomesVeteransVocational rehabilitationAnalysis of the Impact of Antiretroviral Drug Changes on Survival of Patients with Advanced-Stage AIDS with Multidrug-Resistant HIV Infection
Ma R, Jung TH, Peduzzi PN, Brown ST, Kyriakides TC. Analysis of the Impact of Antiretroviral Drug Changes on Survival of Patients with Advanced-Stage AIDS with Multidrug-Resistant HIV Infection. Journal Of The International Association Of Providers Of AIDS Care (JIAPAC) 2019, 18: 2325958219849101. PMID: 31272313, PMCID: PMC6748500, DOI: 10.1177/2325958219849101.Peer-Reviewed Original ResearchConceptsDrug changesCox proportional hazards regression modelKaplan-Meier survival techniqueMultidrug-resistant HIV infectionProportional hazards regression modelsAdvanced-stage AIDSDrug regimen changesSurvival of patientsHazards regression modelsAntiretroviral clinical trialsClinical biomarker dataCause mortalityMedication changesARV regimenHIV infectionImproved survivalRegimen changeClinical outcomesNonclinical reasonsClinical trialsBiomarker changesTreatment historyMultidrug resistanceTherapy strategiesPatients
2018
Prevalence and correlates of depression among caregivers of children living with HIV in Ghana: findings from the Sankofa pediatric disclosure study
Ofori-Atta A, Reynolds NR, Antwi S, Renner L, Nichols JS, Lartey M, Amissah K, Tettey JK, Alhassan A, Ofori IP, Catlin AC, Gan G, Kyriakides TC, Paintsil E, Team O. Prevalence and correlates of depression among caregivers of children living with HIV in Ghana: findings from the Sankofa pediatric disclosure study. AIDS Care 2018, 31: 283-292. PMID: 30360643, PMCID: PMC6382516, DOI: 10.1080/09540121.2018.1537463.Peer-Reviewed Original ResearchConceptsCaregivers of childrenCaregiver depressionCaregivers of HIVLow HIV knowledgeChild health outcomesCorrelates of depressionLow social supportPediatric HIVIllness perceptionsIntervention trialsMean ageHIV knowledgeRisk factorsSevere depressionHigh prevalenceHIV stigmaAdjusted modelHIVCaregiver statusHealth outcomesStudy participantsCaregiversPrevalenceDepressionSub-Saharan countriesHigh prevalence of non-adherence to antiretroviral therapy among undisclosed HIV-infected children in Ghana
Nichols JS, Kyriakides TC, Antwi S, Renner L, Lartey M, Seaneke OA, Obeng R, Catlin AC, Gan G, Reynolds NR, Paintsil E, Team O. High prevalence of non-adherence to antiretroviral therapy among undisclosed HIV-infected children in Ghana. AIDS Care 2018, 31: 25-34. PMID: 30235940, PMCID: PMC6288009, DOI: 10.1080/09540121.2018.1524113.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyART adherence ratesPediatric HIV carePrevalence of adherenceAntiretroviral medication adherenceCohort of childrenHIV-positive statusChildren of caregiversChild-caregiver dyadsHIV carePharmacy recordsRefill dataMedian adherenceMedication adherenceAdherence ratesPoor adherenceHigh prevalencePositive statusIntervention studiesHIVGood adherenceAdherenceBaseline dataChildrenTherapyEfficacy of Extended-Release Naltrexone on HIV-Related and Drinking Outcomes Among HIV-Positive Patients: A Randomized-Controlled Trial
Edelman EJ, Moore BA, Holt SR, Hansen N, Kyriakides TC, Virata M, Brown ST, Justice AC, Bryant KJ, Fiellin DA, Fiellin LE. Efficacy of Extended-Release Naltrexone on HIV-Related and Drinking Outcomes Among HIV-Positive Patients: A Randomized-Controlled Trial. AIDS And Behavior 2018, 23: 211-221. PMID: 30073637, PMCID: PMC6476298, DOI: 10.1007/s10461-018-2241-z.Peer-Reviewed Original ResearchConceptsHIV-positive patientsHeavy drinking daysVACS Index scoreXR-NTXART adherenceDrinking daysIndex scoreUndetectable HIV viral loadCD4 cell countExtended-release naltrexoneDouble-blind placeboHIV viral loadRandomized-controlled trialDrinking outcomesHIV biomarkersSecondary outcomesHIV outcomesPrimary outcomeViral loadAntiretroviral adherenceClinical trialsCell countAlcohol treatmentHIVPatientsEffect of Evidence-Based Supported Employment vs Transitional Work on Achieving Steady Work Among Veterans With Posttraumatic Stress Disorder: A Randomized Clinical Trial
Davis LL, Kyriakides TC, Suris AM, Ottomanelli LA, Mueller L, Parker PE, Resnick SG, Toscano R, Scrymgeour AA, Drake RE. Effect of Evidence-Based Supported Employment vs Transitional Work on Achieving Steady Work Among Veterans With Posttraumatic Stress Disorder: A Randomized Clinical Trial. JAMA Psychiatry 2018, 75: 316-324. PMID: 29490371, PMCID: PMC5875356, DOI: 10.1001/jamapsychiatry.2017.4472.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderClinical trialsIPS groupIndividual PlacementVeterans Affairs Medical CenterCompetitive jobsStress disorderChronic posttraumatic stress disorderVocational rehabilitation interventionsVocational rehabilitationCompetitive employmentMore participantsTreat analysisMean ageMedical CenterMAIN OUTCOMERehabilitation interventionsMultisite trialLatino ethnicityIPS participantsSupported employment interventionTransitional workTrialsVeteransVeterans Individual Placement and Support Towards Advancing Recovery: Methods and Baseline Clinical Characteristics of a Multisite Study
Davis LL, Kyriakides TC, Suris A, Ottomanelli L, Drake RE, Parker PE, Mueller L, Resnick SG, Toscano R, Blansett CM, McCall KP, Huang GD. Veterans Individual Placement and Support Towards Advancing Recovery: Methods and Baseline Clinical Characteristics of a Multisite Study. Psychiatric Rehabilitation Journal 2018, 41: 55-66. PMID: 28358525, DOI: 10.1037/prj0000250.Peer-Reviewed Original ResearchConceptsTransitional work programPosttraumatic stress disorderVeterans Affairs Medical CenterUsual care practicesVeterans Affairs Cooperative Studies ProgramService-connected disabilityYears of ageTrial of IPSCooperative Studies ProgramCombat-related traumaMilitary sexual traumaBaseline characteristicsClinical characteristicsMedical CenterVeteran populationBaseline findingsOutcome criteriaRehabilitation servicesMultisite trialStress disorderPTSD populationsVocational rehabilitation servicesStudy sampleIndividual PlacementSexual trauma
2017
Video Game Intervention for Sexual Risk Reduction in Minority Adolescents: Randomized Controlled Trial
Fiellin LE, Hieftje KD, Pendergrass TM, Kyriakides TC, Duncan LR, Dziura JD, Sawyer BG, Mayes L, Crusto CA, Forsyth BW, Fiellin DA. Video Game Intervention for Sexual Risk Reduction in Minority Adolescents: Randomized Controlled Trial. Journal Of Medical Internet Research 2017, 19: e314. PMID: 28923788, PMCID: PMC5625130, DOI: 10.2196/jmir.8148.Peer-Reviewed Original ResearchConceptsSexual health attitudesHuman immunodeficiency virusIntervention groupHealth attitudesInitiation of intercourseVideo game interventionControl groupHIV sexual riskSexual health outcomesSexual risk reductionDelay of initiationDigital health interventionsSecondary outcomesControlled TrialsGame interventionPrimary outcomeImmunodeficiency virusMean ageAnal intercourseHealth outcomesHealth interventionsSexual riskMonthsMinority adolescentsInterventionMeta-analysis of individual-patient data from EVAR-1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years
Powell J, Sweeting M, Ulug P, Blankensteijn J, Lederle F, Becquemin J, Greenhalgh R, , Greenhalgh R, Beard J, Buxton M, Brown L, Harris P, Powell J, Rose J, Russell I, Sculpher M, Thompson S, Lilford R, Bell P, Greenhalgh R, Whitaker S, Poole‐Wilson T, Ruckley C, Campbell W, Dean M, Ruttley M, Coles E, Powell J, Halliday A, Gibbs S, Brown L, Epstein D, Sculpher M, Thompson S, Hannon R, Johnston L, Bradbury A, Henderson M, Parvin S, Shepherd D, Greenhalgh R, Mitchell A, Edwards P, Abbott G, Higman D, Vohra A, Ashley S, Robottom C, Wyatt M, Rose J, Byrne D, Edwards R, Leiberman D, McCarter D, Taylor P, Reidy J, Wilkinson A, Ettles D, Clason A, Leen G, Wilson N, Downes M, Walker S, Lavelle J, Gough M, McPherson S, Scott D, Kessell D, Naylor R, Sayers R, Fishwick N, Harris P, Gould D, Walker M, Chalmers N, Garnham A, Collins M, Beard J, Gaines P, Ashour M, Uberoi R, Braithwaite B, Whitaker S, Davies J, Travis S, Hamilton G, Platts A, Shandall A, Sullivan B, Sobeh M, Matson M, Fox A, Orme R, Yusef W, Doyle T, Horrocks M, Hardman J, Blair P, Ellis P, Morris G, Odurny A, Vohra R, Duddy M, Thompson M, Loosemore T, Belli A, Morgan R, Adiseshiah M, Brookes J, McCollum C, Ashleigh R, Aukett M, Baker S, Barbe E, Batson N, Bell J, Blundell J, Boardley D, Boyes S, Brown O, Bryce J, Carmichael M, Chance T, Coleman J, Cosgrove C, Curran G, Dennison T, Devine C, Dewhirst N, Errington B, Farrell H, Fisher C, Fulford P, Gough M, Graham C, Hooper R, Horne G, Horrocks L, Hughes B, Hutchings T, Ireland M, Judge C, Kelly L, Kemp J, Kite A, Kivela M, Lapworth M, Lee C, Linekar L, Mahmood A, March L, Martin J, Matharu N, McGuigen K, Morris‐Vincent P, Murray S, Murtagh A, Owen G, Ramoutar V, Rippin C, Rowley J, Sinclair J, Spencer S, Taylor V, Tomlinson C, Ward S, Wealleans V, West J, White K, Williams J, Wilson L, Grobbee D, Blankensteijn J, Bak A, Buth J, Pattynama P, Verhoeven E, van Voorthuisen A, Blankensteijn J, Balm R, Buth J, Cuypers P, Grobbee D, Prinssen M, van Sambeek M, Verhoeven E, Baas A, Hunink M, van Engelshoven J, Jacobs M, de Mol B, van Bockel J, Balm R, Reekers J, Tielbeek X, Verhoeven E, Wisselink W, Boekema N, Heuveling L, Sikking I, Prinssen M, Balm R, Blankensteijn J, Buth J, Cuypers P, van Sambeek M, Verhoeven E, de Bruin J, Baas A, Blankensteijn J, Prinssen M, Buth J, Tielbeek A, Blankensteijn J, Balm R, Reekers J, van Sambeek M, Pattynama P, Verhoeven E, Prins T, van der Ham A, van der Velden J, van Sterkenburg S, ten Haken G, Bruijninckx C, van Overhagen H, Tutein Nolthenius R, Hendriksz T, Teijink J, Odink H, de Smet A, Vroegindeweij D, van Loenhout R, Rutten M, Hamming J, Lampmann L, Bender M, Pasmans H, Vahl A, de Vries C, Mackaay A, van Dortmont L, van der Vliet A, Schultze Kool L, Boomsma J, van Dop H, de Mol van Otterloo J, de Rooij T, Smits T, Yilmaz E, Wisselink W, van den Berg F, Visser M, van der Linden E, Schurink G, de Haan M, Smeets H, Stabel P, van Elst F, Poniewierski J, Vermassen F, Lederle F, Freischlag J, Kohler T, Latts E, Matsumura J, Padberg F, Kyriakides T, Swanson K, Guarino P, Peduzzi P, Antonelli M, Cushing C, Davis E, Durant L, Joyner S, Kossack T, Kyriakides T, LeGwin M, McBride V, O'Connor T, Poulton J, Stratton T, Zellner S, Snodgrass A, Thornton J, Swanson K, Haakenson C, Stroupe K, Jonk Y, Hallett J, Hertzer N, Towne J, Katz D, Karrison T, Matts J, Marottoli R, Kasl S, Mehta R, Feldman R, Farrell W, Allore H, Perry E, Niederman J, Randall F, Zeman M, Beckwith T, O'Leary T, Huang G, Latts E, Bader M, Ketteler E, Kingsley D, Marek J, Massen R, Matteson B, Pitcher J, Langsfeld M, Corson J, Goff J, Kasirajan K, Paap C, Robertson D, Salam A, Veeraswamy R, Milner R, Kasirajan K, Guidot J, Lal B, Busuttil S, Lilly M, Braganza M, Ellis K, Patterson M, Jordan W, Whitley D, Taylor S, Passman M, Kerns D, Inman C, Poirier J, Ebaugh J, Raffetto J, Chew D, Lathi S, Owens C, Hickson K, Dosluoglu H, Eschberger K, Kibbe M, Baraniewski H, Matsumura J, Endo M, Busman A, Meadows W, Evans M, Giglia J, El Sayed H, Reed A, Ruf M, Ross S, Jean‐Claude J, Pinault G, Kang P, White N, Eiseman M, Jones T, Timaran C, Modrall J, Welborn M, Lopez J, Nguyen T, Chacko J, Granke K, Vouyouka A, Olgren E, Chand P, Allende B, Ranella M, Yales C, Whitehill T, Krupski T, Nehler M, Johnson S, Jones D, Strecker P, Bhola M, Shortell C, Gray J, Lawson J, McCann R, Sebastian M, Kistler Tetterton J, Blackwell C, Prinzo P, Lee N, Padberg F, Cerveira J, Lal B, Zickler R, Hauck K, Berceli S, Lee W, Ozaki C, Nelson P, Irwin A, Baum R, Aulivola B, Rodriguez H, Littooy F, Greisler H, O'Sullivan M, Kougias P, Lin P, Bush R, Guinn G, Bechara C, Cagiannos C, Pisimisis G, Barshes N, Pillack S, Guillory B, Cikrit D, Lalka S, Lemmon G, Nachreiner R, Rusomaroff M, O'Brien E, Cullen J, Hoballah J, Sharp W, McCandless J, Beach V, Minion D, Schwarcz T, Kimbrough J, Ashe L, Rockich A, Warner‐Carpenter J, Moursi M, Eidt J, Brock S, Bianchi C, Bishop V, Gordon I, Fujitani R, Kubaska S, Behdad M, Azadegan R, Ma Agas C, Zalecki K, Hoch J, Carr S, Acher C, Schwarze M, Tefera G, Mell M, Dunlap B, Rieder J, Stuart J, Weiman D, Abul‐Khoudoud O, Garrett H, Walsh S, Wilson K, Seabrook G, Cambria R, Brown K, Lewis B, Framberg S, Kallio C, Barke R, Santilli S, d'Audiffret A, Oberle N, Proebstle C, Johnson L, Jacobowitz G, Cayne N, Rockman C, Adelman M, Gagne P, Nalbandian M, Caropolo L, Pipinos I, Johanning J, Lynch T, DeSpiegelaere H, Purviance G, Zhou W, Dalman R, Lee J, Safadi B, Coogan S, Wren S, Bahmani D, Maples D, Thunen S, Golden M, Mitchell M, Fairman R, Reinhardt S, Wilson M, Tzeng E, Muluk S, Peterson N, Foster M, Edwards J, Moneta G, Landry G, Taylor L, Yeager R, Cannady E, Treiman G, Hatton‐Ward S, Salabsky T, Kansal N, Owens E, Estes M, Forbes B, Sobotta C, Rapp J, Reilly L, Perez S, Yan K, Sarkar R, Dwyer S, Perez S, Chong K, Kohler T, Hatsukami T, Glickerman D, Sobel M, Burdick T, Pedersen K, Cleary P, Back M, Bandyk D, Johnson B, Shames M, Reinhard R, Thomas S, Hunter G, Leon L, Westerband A, Guerra R, Riveros M, Mills J, Hughes J, Escalante A, Psalms S, Day N, Macsata R, Sidawy A, Weiswasser J, Arora S, Jasper B, Dardik A, Gahtan V, Muhs B, Sumpio B, Gusberg R, Spector M, Pollak J, Aruny J, Kelly E, Wong J, Vasilas P, Joncas C, Gelabert H, DeVirgillio C, Rigberg D, Cole L, Becquemin J, Marzelle J, Becquemin J, Sapoval M, Becquemin J, Favre J, Watelet J, Lermusiaux P, Sapoval M, Lepage E, Hemery F, Dolbeau G, Hawajry N, Cunin P, Harris P, Stockx L, Chatellier G, Mialhe C, Fiessinger J, Pagny L, Kobeiter H, Boissier C, Lacroix P, Ledru F, Pinot J, Deux J, Tzvetkov B, Duvaldestin P, Watelet J, Jourdain C, David V, Enouf D, Ady N, Krimi A, Boudjema N, Jousset Y, Enon B, Blin V, Picquet J, L'Hoste P, Thouveny F, Borie H, Kowarski S, Pernes J, Auguste M, Becquemin J, Desgranges P, Allaire E, Marzelle J, Kobeiter H, Meaulle P, Chaix D, Juliae P, Fabiani J, Chevalier P, Combes M, Seguin A, Belhomme D, Sapoval M, Baque J, Pellerin O, Favre J, Barral X, Veyret C, Watelet J, Peillon C, Plissonier D, Thomas P, Clavier E, Lermusiaux P, Martinez R, Bleuet F, C D, Verhoye J, Langanay T, Heautot J, Koussa M, Haulon S, Halna P, Destrieux L, Lions C, Wiloteaux S, Beregi J, Bergeron P, Pinot J, Patra P, Costargent A, Chaillou P, D'Alicourt A, Goueffic Y, Cheysson E, Parrot A, Garance P, Demon A, Tyazi A, Pillet J, Lescalie F, Tilly G, Steinmetz E, Favier C, Brenot R, Krause D, Cercueil J, Vahdat O, Sauer M, Soula P, Querian A, Garcia O, Levade M, Colombier D, Cardon J, Joyeux A, Borrelly P, Dogas G, Magnan P, Branchereau A, Bartoli J, Hassen‐Khodja R, Batt M, Planchard P, Bouillanne P, Haudebourg P, Bayne J, Gouny P, Badra A, Braesco J, Nonent M, Lucas A, Cardon A, Kerdiles Y, Rolland Y, Kassab M, Brillu C, Goubault F, Tailboux L, Darrieux H, Briand O, Maillard J, Varty K, Cousins C. Meta-analysis of individual-patient data from EVAR-1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years. British Journal Of Surgery 2017, 104: 166-178. PMID: 28160528, PMCID: PMC5299468, DOI: 10.1002/bjs.10430.Peer-Reviewed Original ResearchConceptsElective endovascular aneurysm repairEarly survival advantageEVAR groupOpen repairIndividual patient dataAbdominal aortic aneurysmSurvival advantageEVAR-1Artery diseaseAortic aneurysmPrevious coronary artery diseaseBrachial pressure indexModerate renal dysfunctionPeripheral artery diseaseCoronary artery diseaseEndovascular aneurysm repairPrespecified analysis planOperative mortalityRenal dysfunctionAneurysm repairEarly mortalityACE trialLower ankleLower mortalityMortality advantage
2016
Long-term Cost-effectiveness in the Veterans Affairs Open vs Endovascular Repair Study of Aortic Abdominal Aneurysm: A Randomized Clinical Trial
Lederle FA, Stroupe KT, Kyriakides TC, Ge L, Freischlag JA. Long-term Cost-effectiveness in the Veterans Affairs Open vs Endovascular Repair Study of Aortic Abdominal Aneurysm: A Randomized Clinical Trial. JAMA Surgery 2016, 151: 1139-1144. PMID: 27627802, DOI: 10.1001/jamasurg.2016.2783.Peer-Reviewed Original ResearchConceptsAbdominal aortic aneurysmOpen repair groupEndovascular repairHealth care costsClinical trialsEndovascular groupRepair groupTotal mean health care costsCare costsVeterans Affairs Medical CenterMean health care costsEndovascular repair proceduresInitial endovascular repairAortic abdominal aneurysmQuality of lifeHealth care servicesElective repairClinical outcomesInitial repairShorter hospitalizationAbdominal aneurysmSecondary proceduresAortic aneurysmMAIN OUTCOMEMedical CenterCharacterizing Patients with Very-Low-Level HIV Viremia: A Community-Based Study
Helou E, Shenoi S, Kyriakides T, Landry ML, Kozal M, Barakat LA. Characterizing Patients with Very-Low-Level HIV Viremia: A Community-Based Study. Journal Of The International Association Of Providers Of AIDS Care (JIAPAC) 2016, 16: 261-266. PMID: 27903948, PMCID: PMC5423832, DOI: 10.1177/2325957416680028.Peer-Reviewed Original ResearchConceptsVirologic failureViral load levelsPill burdenAlcohol useHuman immunodeficiency virus (HIV) careLow-level HIV viremiaUndetectable viral load levelsAntiretroviral regimen changesAntiretroviral therapy changesExperienced virologic failureLow-level viremiaIntravenous drug useSubset of patientsFrequent clinic visitsPoor clinical outcomePossible risk factorsHepatitis C virusHIV viremiaMore comorbiditiesNonfailure groupVirologic suppressionVirological failureCD4 countConsecutive chartsClinic visitsThe design and implementation of a randomized controlled trial of a risk reduction and human immunodeficiency virus prevention videogame intervention in minority adolescents: PlayForward: Elm City Stories
Fiellin LE, Kyriakides TC, Hieftje KD, Pendergrass TM, Duncan LR, Dziura JD, Sawyer BG, Fiellin DA. The design and implementation of a randomized controlled trial of a risk reduction and human immunodeficiency virus prevention videogame intervention in minority adolescents: PlayForward: Elm City Stories. Clinical Trials 2016, 13: 400-408. PMID: 27013483, PMCID: PMC4942329, DOI: 10.1177/1740774516637871.Peer-Reviewed Original ResearchConceptsGame dataHuman immunodeficiency virus (HIV) infectionHuman immunodeficiency virus prevention interventionsPsychosocial antecedentsImmunodeficiency virus infectionRisk behavior reductionVideogame interventionMinority adolescentsBehavioral interventionsRisky sexual behaviorLarge-scale trialsMinority youthControl gameCommunity-based programsPeer pressureAssessment dataSummer campStudy visitBehavior reductionVirus infectionPrevention interventionsGame designersSchool programsAdolescentsEmpiric testing
2015
Predictors and outcomes of endoleaks in the Veterans Affairs Open Versus Endovascular Repair (OVER) Trial of Abdominal Aortic Aneurysms
Lal BK, Zhou W, Li Z, Kyriakides T, Matsumura J, Lederle FA, Freischlag J, Group O. Predictors and outcomes of endoleaks in the Veterans Affairs Open Versus Endovascular Repair (OVER) Trial of Abdominal Aortic Aneurysms. Journal Of Vascular Surgery 2015, 62: 1394-1404. PMID: 26598115, DOI: 10.1016/j.jvs.2015.02.003.Peer-Reviewed Original ResearchConceptsType II endoleakEndovascular repairSecondary interventionsAortic aneurysmRisk factorsAneurysm sizeVeterans AffairsKaplan-Meier survival analysisInitial aneurysm sizeStandard-risk patientsSuccessful endovascular repairType of endoleakVascular risk factorsInfrarenal aortic aneurysmLong-term outcomesAnalysis of patientsLength of survivalAbdominal aortic aneurysmPresence of endoleaksLogistic regression analysisDiameter enlargementOVER trialPatient demographicsEndoleak developmentLong followHIV knowledge, stigma, and illness beliefs among pediatric caregivers in Ghana who have not disclosed their child's HIV status
Paintsil E, Renner L, Antwi S, Dame J, Enimil A, Ofori-Atta A, Alhassan A, Ofori IP, Cong X, Kyriakides T, Reynolds NR. HIV knowledge, stigma, and illness beliefs among pediatric caregivers in Ghana who have not disclosed their child's HIV status. AIDS Care 2015, 27: 18-27. PMID: 26616122, PMCID: PMC4665118, DOI: 10.1080/09540121.2015.1007116.Peer-Reviewed Original ResearchConceptsHIV statusIllness perceptionsUsual careHIV knowledgeTeaching hospitalCaregiver characteristicsBrief HIV Knowledge QuestionnaireKorle-Bu Teaching HospitalKomfo Anokye Teaching HospitalBrief Illness Perception QuestionnaireMultivariable linear regression analysisCaregivers' illness perceptionsChild's HIV statusHigh HIV stigmaHIV Knowledge QuestionnaireMajority of HIVPercent of caregiversHIV-negative statusPediatric HIV disclosureIllness Perception QuestionnaireHIV-positive statusHIV Stigma ScaleBaseline dataLower household incomeMedian ageSankofa pediatric HIV disclosure intervention cyber data management: building capacity in a resource-limited setting and ensuring data quality
Catlin AC, Fernando S, Gamage R, Renner L, Antwi S, Tettey JK, Amisah KA, Kyriakides T, Cong X, Reynolds NR, Paintsil E. Sankofa pediatric HIV disclosure intervention cyber data management: building capacity in a resource-limited setting and ensuring data quality. AIDS Care 2015, 27: 99-107. PMID: 26616131, PMCID: PMC4704410, DOI: 10.1080/09540121.2015.1023246.Peer-Reviewed Original ResearchConceptsCyber infrastructureData explorationOpen-source software platformData elementsData management toolsReal-time supportChallenges of capturingData management teamDatabase accessAccess controlData queryData management capacityDatabase systemsSoftware platformData managementAnalysis needsError checkingSummary viewCommon data elementsData captureData capture toolCapture toolClinical research dataData validationData summaries