2019
Employment Outcomes From VA Vocational Services Involving Transitional Work for Veterans With a Diagnosis of Posttraumatic Stress Disorder
Davis LL, Resnick SG, Maieritsch KP, Weber KC, Erbes CR, Strom TQ, McCall KP, Kyriakides TC. Employment Outcomes From VA Vocational Services Involving Transitional Work for Veterans With a Diagnosis of Posttraumatic Stress Disorder. Psychiatric Rehabilitation Journal 2019, 42: 257-267. PMID: 30945920, PMCID: PMC6910199, DOI: 10.1037/prj0000357.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderVeterans Health AdministrationStress disorderCompetitive employment outcomesStudy of veteransComparative subgroup analysisCompetitive jobsBaseline characteristicsSubgroup analysisHealth AdministrationYounger agePsychiatric disabilitiesTransitional workPotential subgroupsNonengagersOutcomesVeteransVocational rehabilitationAnalysis of the Impact of Antiretroviral Drug Changes on Survival of Patients with Advanced-Stage AIDS with Multidrug-Resistant HIV Infection
Ma R, Jung TH, Peduzzi PN, Brown ST, Kyriakides TC. Analysis of the Impact of Antiretroviral Drug Changes on Survival of Patients with Advanced-Stage AIDS with Multidrug-Resistant HIV Infection. Journal Of The International Association Of Providers Of AIDS Care (JIAPAC) 2019, 18: 2325958219849101. PMID: 31272313, PMCID: PMC6748500, DOI: 10.1177/2325958219849101.Peer-Reviewed Original ResearchConceptsDrug changesCox proportional hazards regression modelKaplan-Meier survival techniqueMultidrug-resistant HIV infectionProportional hazards regression modelsAdvanced-stage AIDSDrug regimen changesSurvival of patientsHazards regression modelsAntiretroviral clinical trialsClinical biomarker dataCause mortalityMedication changesARV regimenHIV infectionImproved survivalRegimen changeClinical outcomesNonclinical reasonsClinical trialsBiomarker changesTreatment historyMultidrug resistanceTherapy strategiesPatients
2018
Effect of Evidence-Based Supported Employment vs Transitional Work on Achieving Steady Work Among Veterans With Posttraumatic Stress Disorder: A Randomized Clinical Trial
Davis LL, Kyriakides TC, Suris AM, Ottomanelli LA, Mueller L, Parker PE, Resnick SG, Toscano R, Scrymgeour AA, Drake RE. Effect of Evidence-Based Supported Employment vs Transitional Work on Achieving Steady Work Among Veterans With Posttraumatic Stress Disorder: A Randomized Clinical Trial. JAMA Psychiatry 2018, 75: 316-324. PMID: 29490371, PMCID: PMC5875356, DOI: 10.1001/jamapsychiatry.2017.4472.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderClinical trialsIPS groupIndividual PlacementVeterans Affairs Medical CenterCompetitive jobsStress disorderChronic posttraumatic stress disorderVocational rehabilitation interventionsVocational rehabilitationCompetitive employmentMore participantsTreat analysisMean ageMedical CenterMAIN OUTCOMERehabilitation interventionsMultisite trialLatino ethnicityIPS participantsSupported employment interventionTransitional workTrialsVeterans
2012
Cost-effectiveness of open versus endovascular repair of abdominal aortic aneurysm in the OVER trial
Stroupe KT, Lederle FA, Matsumura JS, Kyriakides TC, Jonk YC, Ge L, Freischlag JA, Group O. Cost-effectiveness of open versus endovascular repair of abdominal aortic aneurysm in the OVER trial. Journal Of Vascular Surgery 2012, 56: 901-909.e2. PMID: 22640466, DOI: 10.1016/j.jvs.2012.01.086.Peer-Reviewed Original ResearchConceptsTotal health care costsEndovascular repair groupEndovascular groupHealth care providersHealth care costsRepair groupEndovascular repairMean total health care costsCare costsAbdominal aortic aneurysm repairPatient's health care providersVeterans Affairs Cooperative StudyHealth care utilization dataVA Health Economics Resource CenterOpen repair groupAortic aneurysm repairEndovascular AAA repairNon-VA careLength of stayAbdominal aortic aneurysmLower mean costQuality of lifeGraft costsMedicare data sourcesOVER trial
2011
Effect of Treatment Interruption and Intensification of Antiretroviral Therapy on Health-Related Quality of Life in Patients with Advanced HIV
Joyce VR, Barnett PG, Chow A, Bayoumi AM, Griffin SC, Sun H, Holodniy M, Brown ST, Kyriakides TC, Cameron DW, Youle M, Sculpher M, Anis AH, Owens DK. Effect of Treatment Interruption and Intensification of Antiretroviral Therapy on Health-Related Quality of Life in Patients with Advanced HIV. Medical Decision Making 2011, 32: 70-82. PMID: 21383086, DOI: 10.1177/0272989x10397615.Peer-Reviewed Original ResearchConceptsVisual analog scaleHIV patientsART intensificationTreatment interruptionClinical eventsMedical Outcomes Study HIV Health SurveyAdvanced HIV patientsAntiretroviral therapy interruptionMultiple treatment failuresTemporary treatment interruptionAdverse clinical eventsHealth-related qualityStandard ARTHealth Utilities IndexStandard gambleQuality of lifeAdvanced HIVART interruptionInferior HRQoLMDR HIVTherapy interruptionAntiretroviral therapyHIV cohortOpen labelHRQoL scores
2010
Methodological Issues in Comparative Effectiveness Research: Clinical Trials
Peduzzi P, Kyriakides T, O'Connor TZ, Guarino P, Warren SR, Huang GD. Methodological Issues in Comparative Effectiveness Research: Clinical Trials. The American Journal Of Medicine 2010, 123: e8-e15. PMID: 21184867, DOI: 10.1016/j.amjmed.2010.10.003.Peer-Reviewed Original ResearchConceptsComparative effectiveness clinical trialEffectiveness clinical trialClinical trialsVeterans Affairs Cooperative Studies ProgramCooperative Studies ProgramComparative effectiveness researchMechanism of actionUsual careDiabetes mellitusRheumatoid arthritisFuture trialsClinical equipoisePatient preferencesRisk factorsNeurologic disordersInfectious diseasesMental healthTrialsDisease areasEffectiveness researchPharmaceutical issuesType of studyValid comparisonsMellitusArthritis
2009
Health-Related Quality of Life in a Randomized Trial of Antiretroviral Therapy for Advanced HIV Disease
Joyce VR, Barnett PG, Bayoumi AM, Griffin SC, Kyriakides TC, Yu W, Sundaram V, Holodniy M, Brown ST, Cameron W, Youle M, Sculpher M, Anis AH, Owens DK. Health-Related Quality of Life in a Randomized Trial of Antiretroviral Therapy for Advanced HIV Disease. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2009, 50: 27-36. PMID: 19295332, DOI: 10.1097/qai.0b013e31818ce6f3.Peer-Reviewed Original ResearchConceptsHealth Utilities Index Mark 3Treatment-experienced HIV patientsEQ-5DHIV patientsHRQoL scoresClinical variablesMedical Outcomes Study HIV Health SurveyEQ-5D visual analog scaleHealth statusStandard gamblePreference-based health-related qualityAdvanced HIV diseaseBaseline HRQOL scoresConcomitant medication useTreatment-experienced HIVCD4 cell countHIV viral loadHealth-related qualityVisual analog scaleVeterans Affairs hospitalEQ-5D VASCross-sectional studyPreference-based HRQOLQuality of lifeTime trade-off (TTO) technique
2004
Study conduct, monitoring and data management in a trinational trial: the OPTIMA model
Kyriakides TC, Babiker A, Singer J, Piaseczny M, Russo J. Study conduct, monitoring and data management in a trinational trial: the OPTIMA model. Clinical Trials 2004, 1: 277-281. PMID: 16279253, DOI: 10.1191/1740774504cn022oa.Peer-Reviewed Original Research