Six-Minute Walk Test As a Measure of Functional Change after Chemotherapy in Cardiac AL Amyloidosis
Decker I, Ukaegbu O, Goodman S, Lenihan D, Hung R, Kassim A, Harrell S, McDonagh K, Phillips S, Rawling K, Rubinstein S, Sethi T, Cornell R. Six-Minute Walk Test As a Measure of Functional Change after Chemotherapy in Cardiac AL Amyloidosis. Blood 2015, 126: 1841. DOI: 10.1182/blood.v126.23.1841.1841.Peer-Reviewed Original ResearchAutologous hematopoietic cell transplantationBrain natriuretic peptideAL amyloid patientsCardiac responseHeart failureHematological responseCardiac involvementWalk testAmyloid patientsCardiac amyloidNew York Heart Association classManagement of HFStage I/IISix-minute walk testTroponin IMultisystem organ dysfunctionNYHA class 3Trial of patientsHematopoietic cell transplantationVentricular ejection fractionMonoclonal antibody therapyPrimary outcome measureImpact of chemotherapyMedian percent changeCardiac AL amyloidosis