1999
Synaptic Interaction between Hypocretin (Orexin) and Neuropeptide Y Cells in the Rodent and Primate Hypothalamus: A Novel Circuit Implicated in Metabolic and Endocrine Regulations
Horvath T, Diano S, van den Pol A. Synaptic Interaction between Hypocretin (Orexin) and Neuropeptide Y Cells in the Rodent and Primate Hypothalamus: A Novel Circuit Implicated in Metabolic and Endocrine Regulations. Journal Of Neuroscience 1999, 19: 1072-1087. PMID: 9920670, PMCID: PMC6782143, DOI: 10.1523/jneurosci.19-03-01072.1999.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCarrier ProteinsChlorocebus aethiopsEndocrine GlandsFemaleHypothalamusIntracellular Signaling Peptides and ProteinsMaleMetabolismNeural PathwaysNeuronsNeuropeptide YNeuropeptidesOrexin ReceptorsOrexinsRatsRats, Sprague-DawleyReceptors, Cell SurfaceReceptors, G-Protein-CoupledReceptors, LeptinReceptors, NeuropeptideSynapsesConceptsHypothalamic functionCentral regulationHypocretin-containing neuronsLateral hypothalamic cellsLeptin receptor immunoreactivityNeuropeptide Y cellsDirect synaptic contactsNeuropeptide Y systemEndocrine regulationEndocrine processesNPY releaseReceptor immunoreactivityExcitatory actionHypocretin cellsSynaptic contactsArcuate nucleusLateral hypothalamusPrimate hypothalamusLeptin receptorSame neuronsHypothalamic cellsSynaptic regulationAdipose tissueHypocretinNPY
1998
Leptin Receptor Immunoreactivity is Associated with the Golgi Apparatus of Hypothalamic Neurones and Glial Cells
Diano S, Kalra S, Horvath T. Leptin Receptor Immunoreactivity is Associated with the Golgi Apparatus of Hypothalamic Neurones and Glial Cells. Journal Of Neuroendocrinology 1998, 10: 647-650. PMID: 9744481, DOI: 10.1046/j.1365-2826.1998.00261.x.Peer-Reviewed Original ResearchConceptsLeptin receptor immunoreactivityReceptor immunoreactivityPerikaryal membraneGlial cellsGolgi apparatusHypothalamic neuronesCentral nervous systemDifferent second messenger systemsHypothalamic neuronalPeripheral hormonesDentate gyrusSecond messenger systemsEndocrine functionLeptin receptorHypothalamic cellsNervous systemThyroid axisImmunoreactivityCentral mechanismsLeptinIntracellular mechanismsTrans cisternaeNeuronesMessenger systemsPredominant localizationAn Alternate Pathway for Visual Signal Integration into the Hypothalamo-Pituitary Axis: Retinorecipient Intergeniculate Neurons Project to Various Regions of the Hypothalamus and Innervate Neuroendocrine Cells Including Those Producing Dopamine
Horvath TL. An Alternate Pathway for Visual Signal Integration into the Hypothalamo-Pituitary Axis: Retinorecipient Intergeniculate Neurons Project to Various Regions of the Hypothalamus and Innervate Neuroendocrine Cells Including Those Producing Dopamine. Journal Of Neuroscience 1998, 18: 1546-1558. PMID: 9454860, PMCID: PMC6792709, DOI: 10.1523/jneurosci.18-04-01546.1998.Peer-Reviewed Original ResearchConceptsHypothalamo-pituitary axisIntergeniculate leafletNeuroendocrine cellsSuprachiasmatic nucleusHypothalamic dopamine neuronsMedial preoptic areaFenestrated capillariesPopulations of neuronsNeurons projectBilateral enucleationHypothalamic projectionsDistal dendritesRetrograde tracerVentromedial nucleusDopamine neuronsIntraperitoneal injectionProjection sitesPeriventricular nucleusPreoptic areaRetinal fibersTract tracingHypothalamic cellsRetinal axonsSynaptic targetsEfferents