2015
Synaptic lipids in cortical function and psychiatric disorders
Stutz B, Horvath TL. Synaptic lipids in cortical function and psychiatric disorders. EMBO Molecular Medicine 2015, 8: 3-5. PMID: 26671988, PMCID: PMC4718156, DOI: 10.15252/emmm.201505749.Peer-Reviewed Original ResearchConceptsPsychiatric disordersClinical therapeutic strategiesPathophysiologic mechanismsCortical circuitryCortical functionExcitatory neuronsTherapeutic strategiesAnimal modelsReliable biomarkersPsychiatric diseasesPsychiatric consequencesEMBO Molecular MedicinePsychiatric conditionsMillions of peopleHuman subjectsCircuit functionDisordersLipidsMolecular medicinePatientsPathophysiologyEtiologyDiseaseMiceNeurons
2014
A temperature hypothesis of hypothalamus-driven obesity.
Horvath TL, Stachenfeld NS, Diano S. A temperature hypothesis of hypothalamus-driven obesity. The Yale Journal Of Biology And Medicine 2014, 87: 149-58. PMID: 24910560, PMCID: PMC4031788.Commentaries, Editorials and LettersConceptsTreatment of obesityWhite adipose tissueEtiology of obesityBrain temperature controlHealth care systemSustained obesityObesity developmentPeripheral tissuesMetabolic disordersLarge financial burdenObesityAdipose tissueMedical strategiesExcess fatMetabolic centersPsychological symptomsLength of lifeCare systemFinancial burdenMetabolic stateTissueVast majorityPatientsEtiologySymptoms
2010
A Sympathetic View on Free Radicals in Diabetes
Diano S, Horvath TL. A Sympathetic View on Free Radicals in Diabetes. Neuron 2010, 66: 809-811. PMID: 20620864, DOI: 10.1016/j.neuron.2010.06.011.Peer-Reviewed Original ResearchPotential novel therapeutic approachHyperglycemia-induced elevationImpairs synaptic transmissionNovel therapeutic approachesSevere complicationsDiabetic complicationsSympathetic neuronsSynaptic transmissionTherapeutic approachesIssue of NeuronNeuropathyComplicationsDiabetesNeuronsFree radicalsDysautonomiaEtiology
2006
Retinopetal Axons in Mammals: Emphasis on Histamine and Serotonin
Gastinger MJ, Tian N, Horvath T, Marshak DW. Retinopetal Axons in Mammals: Emphasis on Histamine and Serotonin. Current Eye Research 2006, 31: 655-667. PMID: 16877274, PMCID: PMC3351198, DOI: 10.1080/02713680600776119.Peer-Reviewed Original ResearchConceptsRetinopetal axonsEffects of serotoninCentral nervous systemRetina of mammalsDorsal rapheHistaminergic neuronsOptic nervePosterior hypothalamusInner retinaBrain stemRetinal neuronsNervous systemRetinal diseasesAxonsArousal systemNeuronsHistamineAnatomical studyRetinaPerikaryaSerotoninNerveHypothalamusEtiologyRaphe