2023
The E-cigarette or Vaping Product Use–Associated Lung Injury Epidemic: Pathogenesis, Management, and Future Directions: An Official American Thoracic Society Workshop Report
Rebuli M, Rose J, Noël A, Croft D, Benowitz N, Cohen A, Goniewicz M, Larsen B, Leigh N, McGraw M, Melzer A, Penn A, Rahman I, Upson D, Alexander L, Ewart G, Jaspers I, Jordt S, Kligerman S, Loughlin C, McConnell R, Neptune E, Nguyen T, Pinkerton K, Witek T. The E-cigarette or Vaping Product Use–Associated Lung Injury Epidemic: Pathogenesis, Management, and Future Directions: An Official American Thoracic Society Workshop Report. Annals Of The American Thoracic Society 2023, 20: 1-17. PMID: 36584985, PMCID: PMC9819258, DOI: 10.1513/annalsats.202209-796st.Peer-Reviewed Original ResearchConceptsE-cigarettesClinical careOfficial American Thoracic Society Workshop ReportProduct use-associated lung injuryUse-associated lung injuryPublic healthAmerican Thoracic Society workshopSevere pulmonary illnessProspective clinical studyPediatric clinical carePublic health responseElectronic medical recordsBiomarkers of exposureIntegrated electronic medical recordsInjury epidemicLung injuryClinical followCase RegistryPulmonary illnessMedical recordsClinical studiesInhalational toxicityDrug Administration regulationsEVALIExogenous exposure
2020
Transient receptor potential channels in pulmonary chemical injuries and as countermeasure targets
Achanta S, Jordt S. Transient receptor potential channels in pulmonary chemical injuries and as countermeasure targets. Annals Of The New York Academy Of Sciences 2020, 1480: 73-103. PMID: 32892378, PMCID: PMC7933981, DOI: 10.1111/nyas.14472.Peer-Reviewed Original ResearchConceptsChemical injuryTRP channelsNeurogenic inflammatory pathwaysChemical threat agentsMediator of injuryTransient receptor potential channelsTransient receptor potential (TRP) ion channelsIntracellular calcium levelsToxic inhalation hazardPotential ion channelsCough reflexPulmonary injuryPulmonary edemaProinflammatory cellsInflammatory pathwaysPathophysiologic eventsOccupational exposureMucus clearanceCalcium levelsInjuryNonneuronal pathwaysRespiratory systemBroader indicationsPotential channelsInhalation hazard