2009
Intensity of renal replacement therapy in acute kidney injury: perspective from within the Acute Renal Failure Trial Network Study
Palevsky PM, O'Connor TZ, Chertow GM, Crowley ST, Zhang JH, Kellum JA, the US Department of Veterans Affairs/National Institutes of Health Acute Renal Failure Trial Network. Intensity of renal replacement therapy in acute kidney injury: perspective from within the Acute Renal Failure Trial Network Study. Critical Care 2009, 13: 310. PMID: 19678919, PMCID: PMC2750132, DOI: 10.1186/cc7901.Peer-Reviewed Original ResearchConceptsAcute kidney injuryRenal replacement therapyAcute Renal Failure Trial Network studyKidney injuryReplacement therapyStudy therapyRenal supportHealth Acute Renal Failure Trial Network studyVeterans Affairs/National InstitutesCause mortalityIll patientsKidney functionContinuous modalitiesStudy investigatorsOptimal doseClinical practiceTherapyVolume managementInjuryNational InstituteNetwork studiesHypotensionPatientsStudy resultsMortality
2008
Lessons for Successful Study Enrollment from the Veterans Affairs/National Institutes of Health Acute Renal Failure Trial Network Study
Crowley ST, Chertow GM, Vitale J, O'Connor T, Zhang J, Schein RM, Choudhury D, Finkel K, Vijayan A, Paganini E, Palevsky PM, Group F. Lessons for Successful Study Enrollment from the Veterans Affairs/National Institutes of Health Acute Renal Failure Trial Network Study. Clinical Journal Of The American Society Of Nephrology 2008, 3: 955-961. PMID: 18385390, PMCID: PMC2440269, DOI: 10.2215/cjn.05621207.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryBiasClinical Trials as TopicCritical IllnessHemodiafiltrationHumansInformed ConsentIntensive Care UnitsMulticenter Studies as TopicNational Institutes of Health (U.S.)Patient SelectionRandomized Controlled Trials as TopicRenal DialysisResearch DesignTreatment OutcomeUnited StatesUnited States Department of Veterans AffairsConceptsHealth Acute Renal Failure Trial Network studyAcute Renal Failure Trial Network studyVeterans Affairs/National InstitutesAcute kidney injuryEnrollment windowKidney injuryPhysician refusalPotential patientsChronic kidney diseaseRenal replacement therapyNational InstituteEnrollment efficiencyLoss of patientsEligible patientsUnderlying comorbiditiesIll patientsStudy enrollmentKidney diseaseReplacement therapyFuture trialsIntervention trialsClinical equipoiseChronic illnessClinical trialsInclusion criteria