Intensity of Renal Support in Critically Ill Patients with Acute Kidney Injury
Palevsky P, Zhang J, O'Connor T, Chertow G, Crowley S, Choudhury D, Finkel K, Kellum J, Paganini E, Schein R, Smith M, Swanson K, Thompson B, Vijayan A, Watnick S, Star R, Peduzzi P. Intensity of Renal Support in Critically Ill Patients with Acute Kidney Injury. New England Journal Of Medicine 2008, 359: 7-20. PMID: 18492867, PMCID: PMC2574780, DOI: 10.1056/nejmoa0802639.Peer-Reviewed Original ResearchConceptsAcute kidney injuryRenal replacement therapyNonrenal organ failureContinuous venovenous hemodiafiltrationIntensive treatment strategiesKidney injuryIll patientsIntensive therapyIntermittent hemodialysisKidney functionOrgan failureRenal supportTreatment strategiesContinuous renal replacement therapyDay 60Intensive renal replacement therapyIntensive renal supportLow-efficiency dialysisCritically Ill PatientsPrimary end pointHemodialysis three timesRate of deathNonrenal organsBaseline characteristicsStable patients