Intracoronary dual-modal optical coherence tomography-near-infrared fluorescence structural–molecular imaging with a clinical dose of indocyanine green for the assessment of high-risk plaques and stent-associated inflammation in a beating coronary artery
Kim S, Lee M, Kim T, Song J, Nam H, Cho H, Jang S, Ryu J, Oh D, Gweon D, Park S, Park K, Oh W, Yoo H, Kim J. Intracoronary dual-modal optical coherence tomography-near-infrared fluorescence structural–molecular imaging with a clinical dose of indocyanine green for the assessment of high-risk plaques and stent-associated inflammation in a beating coronary artery. European Heart Journal 2016, 37: 2833-2844. PMID: 26787442, DOI: 10.1093/eurheartj/ehv726.Peer-Reviewed Original ResearchConceptsHigh-risk plaquesCoronary arteryOptical coherence tomographyIndocyanine greenClinical doseCoherence tomographySwine coronary arteriesLipid-rich plaquesNIRF signalStent-associated complicationsSaline-injected controlsStrong NIRF signalPlaque inflammationPlaque disruptionDES deploymentCoronary imagingFibrous plaquesHuman plaquesInflammationICG uptakeYucatan minipigsPlaquesArteryHistological validationStent struts