2023
Magnetic resonance imaging modalities aid in the differential diagnosis of atypical parkinsonian syndromes
Tinaz S. Magnetic resonance imaging modalities aid in the differential diagnosis of atypical parkinsonian syndromes. Frontiers In Neurology 2023, 14: 1082060. PMID: 36816565, PMCID: PMC9932598, DOI: 10.3389/fneur.2023.1082060.Peer-Reviewed Original ResearchAtypical parkinsonian syndromesParkinsonian syndromesParkinson's diseaseIdiopathic Parkinson's diseaseDisease courseClinical manifestationsDifferential diagnosisTimely diagnosisModalities aidDiagnostic criteriaClinical practiceMRI toolsMagnetic resonance imaging (MRI) technologyNuclear imagingDiagnosisDiagnostic useSyndromeMRI modalitiesDiseaseDiagnostic purposesModalitiesStroke in Parkinson’s disease: a review of epidemiological studies and potential pathophysiological mechanisms
Elfil M, Bayoumi A, Sayed A, Aladawi M, Aboutaleb P, Grieb L, Tolba H, Tinaz S. Stroke in Parkinson’s disease: a review of epidemiological studies and potential pathophysiological mechanisms. Acta Neurologica Belgica 2023, 123: 773-783. PMID: 36710306, DOI: 10.1007/s13760-023-02202-4.Peer-Reviewed Original ResearchConceptsParkinson's diseaseEpidemiological studiesNeurological disordersRate of PDCumulative cardiovascular riskRisk of strokePost-stroke complicationsPotential pathophysiological mechanismsRecent epidemiological studiesQuality of lifeCardiovascular riskIschemic insultPathophysiological mechanismsPD patientsNeurological causesEtiological factorsSleep disordersMotor impairmentStrokeDiseasePathological processesDisordersRiskReviewMorbidity
2018
Functional Magnetic Resonance Imaging-Based Neurofeedback Training in Patients with Parkinson’s Disease (P3.075)
Tinaz S, Nalamada K, Sezgin M, Vives-Rodriguez A, Para K, Scheinost D, Louis E, Hampson M. Functional Magnetic Resonance Imaging-Based Neurofeedback Training in Patients with Parkinson’s Disease (P3.075). Neurology 2018, 90 DOI: 10.1212/wnl.90.15_supplement.p3.075.Peer-Reviewed Original Research
2016
Changes in functional organization and white matter integrity in the connectome in Parkinson's disease
Tinaz S, Lauro PM, Ghosh P, Lungu C, Horovitz SG. Changes in functional organization and white matter integrity in the connectome in Parkinson's disease. NeuroImage Clinical 2016, 13: 395-404. PMID: 28116232, PMCID: PMC5226806, DOI: 10.1016/j.nicl.2016.12.019.Peer-Reviewed Original ResearchConceptsParkinson's diseaseWhite matter integrityPD patientsPD groupWhite matter connectivity changesResting-state functional MRINon-demented PD patientsEarly disease stagesCortico-striatal circuitsWhite matter connectivityDopaminergic medicationDorsal attention networkDisease stageFunctional organizationSensorimotor networkWhole-brain connectomeFunctional modular organizationWhite matterFunctional MRIConnectivity changesDiseasePatientsDiffusion tensorDefault modeBrain connectomeSequence Effect in Parkinson’s Disease Is Related to Motor Energetic Cost
Tinaz S, Pillai AS, Hallett M. Sequence Effect in Parkinson’s Disease Is Related to Motor Energetic Cost. Frontiers In Neurology 2016, 7: 83. PMID: 27252678, PMCID: PMC4877367, DOI: 10.3389/fneur.2016.00083.Peer-Reviewed Original ResearchParkinson's diseaseDopaminergic treatmentIsometric motor tasksVisual feedbackMotor symptomsPD patientsExternal cueingMedication statusPatientsMotor outputRepetitive movementsMajor causeMotor tasksDiseaseHighest motor costMotor plansBradykinesiaMotor controlMotor vigorMotivational cuesRapid decrementTreatmentMorbidityMixed resultsControl