Schwann cells modulate sodium channel expression in spinal sensory neurons in vitro
Hinson AW, Gu XQ, Dib‐Hajj S, Black JA, Waxman SG. Schwann cells modulate sodium channel expression in spinal sensory neurons in vitro. Glia 1997, 21: 339-349. PMID: 9419009, DOI: 10.1002/(sici)1098-1136(199712)21:4<339::aid-glia1>3.0.co;2-z.Peer-Reviewed Original ResearchConceptsDRG neuronsSC-conditioned mediumSodium channel alphaE15 ratsSodium channelsChannel alphaSodium channel immunoreactivitySpinal sensory neuronsBeta2 subunit mRNASodium channel mRNASodium channel expressionFunctional sodium channelsSodium current densityBeta-subunit mRNAChannel immunoreactivityBeta2 mRNASensory neuronsClamp recordingsChannel expressionChannel mRNAIsoform-specific riboprobesNeuronsBeta1RatsHybridization signalsNaG: A sodium channel‐like mRNA shared by Schwann cells and other neural crest derivatives
Felts PA, Black JA, Dib‐Hajj S, Waxman SG. NaG: A sodium channel‐like mRNA shared by Schwann cells and other neural crest derivatives. Glia 1997, 21: 269-276. PMID: 9383036, DOI: 10.1002/(sici)1098-1136(199711)21:3<269::aid-glia2>3.0.co;2-0.Peer-Reviewed Original ResearchConceptsNeural crest originSchwann cellsGanglion neuronsNeural crest derivativesRat dorsal root ganglion neuronsAdrenal medulla chromaffin cellsDorsal root ganglion neuronsSuperior cervical ganglion neuronsSodium channelsCrest derivativesNeural crestNeuronal cell typesAfferent neuronsAfferent functionSitu hybridizationSensory neuronsNeural elementsSensory functionChromaffin cellsNAG mRNANeuronsRT-PCRNAGCell typesPresent study