Biological significance of insulin-like growth factor binding proteins
Weinzimer S, Cohen P. Biological significance of insulin-like growth factor binding proteins. NeuroImmune Biology 2002, 2: 37-65. DOI: 10.1016/s1567-7443(02)80007-2.Peer-Reviewed Original ResearchInsulin-like growth factorGrowth factorFree insulin-like growth factorIGF/IGFBP axisCleavage of IGFBPsIGF-dependent actionsIGF-independent actionsPotent mitogenic agentsIGFBP axisIGFBP proteasesIGF receptorInflammatory diseasesIGFBPsGrowth disordersMitogenic agentsCellular proliferationCell growthSomatic growthHigh affinityPathophysiologyCancerProteinFactorsDiseaseBiological significance