The Impact of Insulin Pharmacokinetics and Pharmacodynamics on the Closed-loop Artificial Pancreas
Lee J, Dassau E, Zisser H, Tamborlane W, Weinzimer S, Doyle F. The Impact of Insulin Pharmacokinetics and Pharmacodynamics on the Closed-loop Artificial Pancreas. 2013, 127-132. DOI: 10.1109/cdc.2013.6759870.Peer-Reviewed Original ResearchInsulin delivery optionsPK/PD characteristicsClinical performanceArtificial pancreasPK/PDMeal disturbance rejectionClosed-loop artificial pancreasPharmacodynamic characteristicsClinical resultsGlucose regulationInsulin pharmacokineticsDelivery optionsPancreasOptionsUniversity of VirginiaMetabolic simulatorPharmacodynamicsPharmacokinetics