The IGF Axis in the Male Reproductive System
Weinzimer S, Cohen P. The IGF Axis in the Male Reproductive System. Contemporary Endocrinology 1999, 407-423. DOI: 10.1007/978-1-59259-712-3_18.Peer-Reviewed Original ResearchBenign prostatic hypertrophyIGF systemIGF receptorInsulin-like growth factor (IGF) systemAbnormal prostate growthGrowth factor systemMale reproductive systemIGF axisProstate growthProstatic hypertrophyProstatic carcinomaCommon conditionUrinary systemAutocrine interactionsObstructive conditionsHealthy prostateImportant cellsPeptide hormonesReproductive systemFactor systemIGFHypertrophyMetabolic functionsCell growthCarcinomaCellular Actions of Insulin-Like Growth Factor Binding Proteins
Ferry R, Katz L, Grimberg A, Cohen P, Weinzimer S. Cellular Actions of Insulin-Like Growth Factor Binding Proteins. Hormone And Metabolic Research 1999, 31: 192-202. PMID: 10226802, PMCID: PMC4151550, DOI: 10.1055/s-2007-978719.Peer-Reviewed Original ResearchConceptsInsulin-like growth factorFree insulin-like growth factorInsulin-like growth factor binding proteinGrowth factorCleavage of IGFBPsIGF-dependent actionsGrowth factor binding proteinFactor binding proteinPotent mitogenic agentsIGFBP proteasesIGF axisIGF receptorIGFBPsCellular actionsMitogenic agentsModulate levelsCellular proliferationCell growthBinding proteinSomatic growthHigh affinityProteinReceptors