Ibuprofen impairs capsulolabral healing in a rat model of anterior glenohumeral instability
Packer JD, Varthi AG, Zhu DS, Javier FG, Young JD, Garver JV, Henry H, Tommasini SM, Blaine TA. Ibuprofen impairs capsulolabral healing in a rat model of anterior glenohumeral instability. Journal Of Shoulder And Elbow Surgery 2017, 27: 315-324. PMID: 29195899, DOI: 10.1016/j.jse.2017.09.027.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnti-Inflammatory Agents, Non-SteroidalDisease Models, AnimalIbuprofenJoint InstabilityMalePostoperative PeriodRange of Motion, ArticularRatsRats, Inbred LewShoulder DislocationShoulder JointWound HealingConceptsNonsteroidal anti-inflammatory drugsNSAID groupGlenohumeral dislocationRat modelControl groupUninjured limbUse of NSAIDsGlenohumeral instabilityGlenoid labrumAnterior glenohumeral dislocationAnterior-inferior labral tearsAnterior glenohumeral instabilityAnti-inflammatory drugsMatched pair analysisNew rat modelPersistent shoulder instabilityCapsular healingPostinjury administrationInjured limbImpaired healingLabral tearsHistologic analysisShoulder instabilityGlenohumeral stabilityBiomechanical testing