2017
Ibuprofen impairs capsulolabral healing in a rat model of anterior glenohumeral instability
Packer JD, Varthi AG, Zhu DS, Javier FG, Young JD, Garver JV, Henry H, Tommasini SM, Blaine TA. Ibuprofen impairs capsulolabral healing in a rat model of anterior glenohumeral instability. Journal Of Shoulder And Elbow Surgery 2017, 27: 315-324. PMID: 29195899, DOI: 10.1016/j.jse.2017.09.027.Peer-Reviewed Original ResearchConceptsNonsteroidal anti-inflammatory drugsNSAID groupGlenohumeral dislocationRat modelControl groupUninjured limbUse of NSAIDsGlenohumeral instabilityGlenoid labrumAnterior glenohumeral dislocationAnterior-inferior labral tearsAnterior glenohumeral instabilityAnti-inflammatory drugsMatched pair analysisNew rat modelPersistent shoulder instabilityCapsular healingPostinjury administrationInjured limbImpaired healingLabral tearsHistologic analysisShoulder instabilityGlenohumeral stabilityBiomechanical testing
2011
Changes in intracortical microporosities induced by pharmaceutical treatment of osteoporosis as detected by high resolution micro-CT
Tommasini SM, Trinward A, Acerbo AS, De Carlo F, Miller LM, Judex S. Changes in intracortical microporosities induced by pharmaceutical treatment of osteoporosis as detected by high resolution micro-CT. Bone 2011, 50: 596-604. PMID: 22226688, PMCID: PMC3278519, DOI: 10.1016/j.bone.2011.12.012.Peer-Reviewed Original ResearchConceptsAge-matched controlsUntreated OVXEstrogen withdrawalSix-month-old female SpragueDifferent osteoporosis treatmentsUntreated OVX ratsStart of treatmentEndosteal regionOsteocyte lacunar sizeEffect of treatmentOVX ratsOsteoporosis treatmentFemale SpraguePTH treatmentDawley ratsCurrent treatmentNumber of lacunaeMedial cortexOsteocyte lacunaePharmaceutical treatmentOVXMedial quadrantAlendronateBone strengthFemoral diaphysis